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MOUSE:CMAH

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Cmah
Protein Name(s) Cytidine monophosphate-N-acetylneuraminic acid hydroxylase

CMP-N-acetylneuraminic acid hydroxylase CMP-N-acetylneuraminate monooxygenase CMP-Neu5Ac hydroxylase CMP-NeuAc hydroxylase

External Links
UniProt Q61419
EMBL D21826
AB061276
AB061277
AB061346
AL589744
BC055079
CCDS CCDS26376.1
PIR A57469
RefSeq NP_001104580.1
NP_001271448.1
NP_001271449.1
NP_031743.3
XP_006516601.1
XP_006516602.1
UniGene Mm.8396
ProteinModelPortal Q61419
STRING 10090.ENSMUSP00000106021
PhosphoSite Q61419
PaxDb Q61419
PRIDE Q61419
Ensembl ENSMUST00000050859
ENSMUST00000110391
ENSMUST00000167746
GeneID 12763
KEGG mmu:12763
UCSC uc007pvq.2
uc011yxn.1
CTD 12763
MGI MGI:103227
eggNOG NOG74230
GeneTree ENSGT00390000010830
HOGENOM HOG000111807
HOVERGEN HBG051000
InParanoid Q61419
KO K08080
OMA PSREHPY
OrthoDB EOG71P29R
PhylomeDB Q61419
TreeFam TF331273
BioCyc MetaCyc:MONOMER-14525
SABIO-RK Q61419
UniPathway UPA00628
NextBio 282114
PRO PR:Q61419
Proteomes UP000000589
Bgee Q61419
Genevestigator Q61419
GO GO:0005737
GO:0005783
GO:0051537
GO:0030338
GO:0046872
GO:0046381
GO:0006054
Gene3D 2.102.10.10
3.60.15.10
InterPro IPR001279
IPR027033
IPR017941
PANTHER PTHR15032:SF10
Pfam PF00355
SUPFAM SSF50022
SSF56281
PROSITE PS51296

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0030338

CMP-N-acetylneuraminate monooxygenase activity

PMID:21987817[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

GO:0030338

CMP-N-acetylneuraminate monooxygenase activity

PMID:21987817[1]

ECO:0000314

F

Figure 2A

complete
CACAO 2454

enables

GO:0030338

CMP-N-acetylneuraminate monooxygenase activity

PMID:22692205[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0046381

CMP-N-acetylneuraminate metabolic process

PMID:7608218[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0030338

CMP-N-acetylneuraminate monooxygenase activity

PMID:7608218[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:7608218[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017941
InterPro:IPR036922

F

Seeded From UniProt

complete

enables

GO:0051537

2 iron, 2 sulfur cluster binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017941
InterPro:IPR036922

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017941
InterPro:IPR036922

P

Seeded From UniProt

complete

enables

GO:0030338

CMP-N-acetylneuraminate monooxygenase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.14.18.2

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037
GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0249
UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005783

endoplasmic reticulum

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0256
UniProtKB-SubCell:SL-0095

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0411

F

Seeded From UniProt

complete

enables

GO:0051537

2 iron, 2 sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0001

F

Seeded From UniProt

complete

involved_in

GO:0006054

N-acetylneuraminate metabolic process

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00628

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Ghaderi, D et al. (2011) Sexual selection by female immunity against paternal antigens can fix loss of function alleles. Proc. Natl. Acad. Sci. U.S.A. 108 17743-8 PubMed GONUTS page
  2. Bergfeld, AK et al. (2012) Metabolism of vertebrate amino sugars with N-glycolyl groups: elucidating the intracellular fate of the non-human sialic acid N-glycolylneuraminic acid. J. Biol. Chem. 287 28865-81 PubMed GONUTS page
  3. 3.0 3.1 3.2 Kawano, T et al. (1995) Molecular cloning of cytidine monophospho-N-acetylneuraminic acid hydroxylase. Regulation of species- and tissue-specific expression of N-glycolylneuraminic acid. J. Biol. Chem. 270 16458-63 PubMed GONUTS page