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MOUSE:CD59B

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Cd59b
Protein Name(s) CD59B glycoprotein

MAC-inhibitory protein MAC-IP Membrane attack complex inhibition factor MACIF Protectin

External Links
UniProt P58019
EMBL AF292401
BX640578
BX813317
BX813317
BX640578
BC139203
BC145912
BC171969
CCDS CCDS16486.1
RefSeq NP_862906.1
XP_006499865.1
XP_006499866.1
XP_006499867.1
XP_006499868.1
UniGene Mm.359026
ProteinModelPortal P58019
SMR P58019
PhosphoSite P58019
PRIDE P58019
Ensembl ENSMUST00000090429
ENSMUST00000111130
ENSMUST00000129749
GeneID 333883
KEGG mmu:333883
UCSC uc008ljn.1
CTD 333883
MGI MGI:1888996
eggNOG NOG83475
GeneTree ENSGT00390000016309
HOGENOM HOG000232180
HOVERGEN HBG005284
InParanoid P58019
KO K04008
OMA NKAAFSI
PhylomeDB P58019
TreeFam TF338524
Reactome REACT_198562
NextBio 400074
PRO PR:P58019
Proteomes UP000000589
CleanEx MM_CD59B
ExpressionAtlas P58019
Genevestigator P58019
GO GO:0031225
GO:0009986
GO:0005576
GO:0005886
GO:0001848
GO:0001775
GO:0007166
GO:0001971
GO:0045916
GO:0045918
InterPro IPR027101
IPR016054
IPR001526
PANTHER PTHR10036:SF6
Pfam PF00021
SMART SM00134

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0009986

cell surface

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1888996
PANTHER:PTN000004112
UniProtKB:P13987

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000004112
RGD:2311

C

Seeded From UniProt

complete

enables

GO:0001848

complement binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000004112
RGD:2311

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1903660

negative regulation of complement-dependent cytotoxicity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2311

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045916

negative regulation of complement activation

PMID:10946279[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0043218

compact myelin

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2311

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043066

negative regulation of apoptotic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2311

P

Seeded From UniProt

complete

part_of

GO:0042383

sarcolemma

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2311

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0042102

positive regulation of T cell proliferation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2311

P

Seeded From UniProt

complete

part_of

GO:0031362

anchored component of external side of plasma membrane

GO_REF:0000008

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P13987

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:11471050[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:10946279[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P13987

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:11485913[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2311

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2311

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001971

negative regulation of activation of membrane attack complex

PMID:11471050[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001971

negative regulation of activation of membrane attack complex

PMID:10946279[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001971

negative regulation of activation of membrane attack complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2311

P

Seeded From UniProt

complete

enables

GO:0001848

complement binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:2311

F

Seeded From UniProt

complete

involved_in

GO:0001971

negative regulation of activation of membrane attack complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027101

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0031225

anchored component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0336

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 Qian, YM et al. (2000) Identification and functional characterization of a new gene encoding the mouse terminal complement inhibitor CD59. J. Immunol. 165 2528-34 PubMed GONUTS page
  3. 3.0 3.1 Qin, X et al. (2001) Genomic structure, functional comparison, and tissue distribution of mouse Cd59a and Cd59b. Mamm. Genome 12 582-9 PubMed GONUTS page
  4. Pillebout, E et al. (2001) Proliferation and remodeling of the peritubular microcirculation after nephron reduction: association with the progression of renal lesions. Am. J. Pathol. 159 547-60 PubMed GONUTS page