MOUSE:CCD66

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Ccdc66
Protein Name(s)	Coiled-coil domain-containing protein 66
External Links
UniProt	Q6NS45
EMBL	AK053185 AK087583 AK145297 AK158666 BC070471 BC072583
CCDS	CCDS36843.1
RefSeq	NP_796085.3 XP_006519190.1 XP_006519191.1 XP_006519194.1
UniGene	Mm.247767 Mm.390701
PhosphoSite	Q6NS45
PaxDb	Q6NS45
PRIDE	Q6NS45
Ensembl	ENSMUST00000050480
GeneID	320234
KEGG	mmu:320234
UCSC	uc007stw.2 uc011zhw.2
CTD	285331
MGI	MGI:2443639
eggNOG	NOG82179
GeneTree	ENSGT00390000012411
HOGENOM	HOG000111429
HOVERGEN	HBG107617
InParanoid	Q6NS45
OMA	LFQTMQR
OrthoDB	EOG7TXKFZ
PhylomeDB	Q6NS45
TreeFam	TF350489
NextBio	396317
PRO	PR:Q6NS45
Proteomes	UP000000589
Bgee	Q6NS45
CleanEx	MM_CCDC66
Genevestigator	Q6NS45
GO	GO:0060060 GO:0046548

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0050908	detection of light stimulus involved in visual perception	PMID:21680557^[1]	ECO:0000315			P		Figure 3: Ccdc66 -/- mouse at 3 months revealed a reduced a-wave amplitude under scotopic conditions and a reduced b-wave amplitude under photopic conditions on a background intensity of 25 cd/m^2.	complete CACAO 4362
part_of	GO:0001917	photoreceptor inner segment	PMID:19777273^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0001895	retina homeostasis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:F1PZQ5	P		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	PMID:19777273^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0036064	ciliary basal body	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:A2RUB6	C		Seeded From UniProt	complete
part_of	GO:0034451	centriolar satellite	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:A2RUB6	C		Seeded From UniProt	complete
part_of	GO:0005929	cilium	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:A2RUB6	C		Seeded From UniProt	complete
part_of	GO:0005874	microtubule	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:A2RUB6	C		Seeded From UniProt	complete
part_of	GO:0005813	centrosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:A2RUB6	C		Seeded From UniProt	complete
enables	GO:0008017	microtubule binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:A2RUB6	F		Seeded From UniProt	complete
involved_in	GO:1903564	regulation of protein localization to cilium	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:A2RUB6	P		Seeded From UniProt	complete
involved_in	GO:0060271	cilium assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:A2RUB6	P		Seeded From UniProt	complete
involved_in	GO:0001578	microtubule bundle formation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:A2RUB6	P		Seeded From UniProt	complete
involved_in	GO:0050908	detection of light stimulus involved in visual perception	PMID:21680557^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1903564	regulation of protein localization to cilium	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:A2RUB6	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060271	cilium assembly	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:A2RUB6	P		Seeded From UniProt	complete
part_of	GO:0036064	ciliary basal body	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:A2RUB6	C		Seeded From UniProt	complete
part_of	GO:0034451	centriolar satellite	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:A2RUB6	C		Seeded From UniProt	complete
enables	GO:0008017	microtubule binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:A2RUB6	F		Seeded From UniProt	complete
part_of	GO:0005929	cilium	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:A2RUB6	C		Seeded From UniProt	complete
part_of	GO:0005874	microtubule	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:A2RUB6	C		Seeded From UniProt	complete
part_of	GO:0005813	centrosome	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:A2RUB6	C		Seeded From UniProt	complete
part_of	GO:0001917	photoreceptor inner segment	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:A2RUB6	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001578	microtubule bundle formation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:A2RUB6	P		Seeded From UniProt	complete
involved_in	GO:1903564	regulation of protein localization to cilium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A2RUB6 ensembl:ENSP00000378167	P		Seeded From UniProt	complete
involved_in	GO:0060271	cilium assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A2RUB6 ensembl:ENSP00000378167	P		Seeded From UniProt	complete
part_of	GO:0036064	ciliary basal body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A2RUB6 ensembl:ENSP00000378167	C		Seeded From UniProt	complete
part_of	GO:0034451	centriolar satellite	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A2RUB6 ensembl:ENSP00000378167	C		Seeded From UniProt	complete
enables	GO:0008017	microtubule binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A2RUB6 ensembl:ENSP00000378167	F		Seeded From UniProt	complete
part_of	GO:0005929	cilium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A2RUB6 ensembl:ENSP00000378167	C		Seeded From UniProt	complete
part_of	GO:0005874	microtubule	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A2RUB6 ensembl:ENSP00000378167	C		Seeded From UniProt	complete
part_of	GO:0005813	centrosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A2RUB6 ensembl:ENSP00000378167	C		Seeded From UniProt	complete
part_of	GO:0001917	photoreceptor inner segment	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A2RUB6 ensembl:ENSP00000378167	C		Seeded From UniProt	complete
involved_in	GO:0001578	microtubule bundle formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A2RUB6 ensembl:ENSP00000378167	P		Seeded From UniProt	complete
part_of	GO:0005813	centrosome	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR039183	C		Seeded From UniProt	complete
enables	GO:0008017	microtubule binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR039183	F		Seeded From UniProt	complete
involved_in	GO:0046548	retinal rod cell development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR039183	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060060	post-embryonic retina morphogenesis in camera-type eye	PMID:21680557^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3893603	P	has_participant:(EMAPA:35688)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046548	retinal rod cell development	PMID:21680557^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3893603	P	occurs_in:(EMAPA:35688) results_in_development_of:(CL:0000604)	Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0966	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C		Seeded From UniProt	complete
part_of	GO:0005929	cilium	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0969 UniProtKB-SubCell:SL-0066	C		Seeded From UniProt	complete
part_of	GO:0005856	cytoskeleton	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0206	C		Seeded From UniProt	complete
involved_in	GO:0030030	cell projection organization	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0970	P		Seeded From UniProt	complete
part_of	GO:0001917	photoreceptor inner segment	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0457	C		Seeded From UniProt	complete
part_of	GO:0005815	microtubule organizing center	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0048	C		Seeded From UniProt	complete
part_of	GO:0001750	photoreceptor outer segment	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0458	C		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Gerding, WM et al. (2011) Ccdc66 null mutation causes retinal degeneration and dysfunction. Hum. Mol. Genet. 20 3620-31 PubMed GONUTS page
↑ ^2.0 ^2.1 Dekomien, G et al. (2010) Progressive retinal atrophy in Schapendoes dogs: mutation of the newly identified CCDC66 gene. Neurogenetics 11 163-74 PubMed GONUTS page

[PMID:21680557-1] 1.0 ^1.1 ^1.2 ^1.3 Gerding, WM et al. (2011) Ccdc66 null mutation causes retinal degeneration and dysfunction. Hum. Mol. Genet. 20 3620-31 PubMed GONUTS page

[PMID:19777273-2] 2.0 ^2.1 Dekomien, G et al. (2010) Progressive retinal atrophy in Schapendoes dogs: mutation of the newly identified CCDC66 gene. Neurogenetics 11 163-74 PubMed GONUTS page

[1]

[2]

MOUSE:CCD66

Contents

Annotations

Notes

References

c

d

e

g

m

p

r

s

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools