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MOUSE:ARP21

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Arpp21 (synonyms: Rcs, Tarpp)
Protein Name(s) cAMP-regulated phosphoprotein 21

ARPP-21 Regulator of calmodulin signaling Thymocyte cAMP-regulated phosphoprotein

External Links
UniProt Q9DCB4
EMBL AF324451
AK002950
AK029467
AK032417
AK032543
AK045507
AK050613
AK137974
BC027107
BC053001
BC128376
CCDS CCDS23587.1
CCDS40786.1
CCDS52943.1
CCDS52944.1
CCDS52945.1
CCDS52946.1
RefSeq NP_001171086.1
NP_001171087.1
NP_001171088.1
NP_001171089.1
NP_001171090.1
NP_001171091.1
NP_001171094.1
NP_083031.1
NP_150289.1
XP_006512407.1
XP_006512411.1
XP_006512413.1
XP_006512414.1
XP_006512424.1
XP_006512425.1
XP_017169139.1
XP_017169140.1
XP_017169141.1
XP_017169142.1
XP_017169146.1
XP_017169148.1
XP_017169149.1
XP_017169152.1
UniGene Mm.297444
Mm.487515
ProteinModelPortal Q9DCB4
SMR Q9DCB4
iPTMnet Q9DCB4
PhosphoSitePlus Q9DCB4
PeptideAtlas Q9DCB4
PRIDE Q9DCB4
Ensembl ENSMUST00000035085
ENSMUST00000070218
ENSMUST00000111872
ENSMUST00000161412
ENSMUST00000162065
ENSMUST00000162097
ENSMUST00000164754
ENSMUST00000172380
ENSMUST00000178410
GeneID 74100
KEGG mmu:74100
UCSC uc009rvx.2
uc009rvy.2
uc009rvz.2
uc009rwa.2
uc009rwc.2
uc009rwe.2
uc009rwf.1
uc009rwg.2
CTD 10777
MGI MGI:107562
GeneTree ENSGT00440000038338
HOVERGEN HBG052192
InParanoid Q9DCB4
OMA PMTQGSQ
OrthoDB EOG091G016L
PhylomeDB Q9DCB4
TreeFam TF315915
ChiTaRS Arpp21
PRO PR:Q9DCB4
Proteomes UP000000589
Bgee ENSMUSG00000032503
CleanEx MM_ARPP21
ExpressionAtlas Q9DCB4
Genevisible Q9DCB4
GO GO:0005737
GO:0005516
GO:0003676
GO:0034605
Gene3D 3.30.1370.50
InterPro IPR001374
IPR036867
IPR024771
Pfam PF01424
PF12752
SMART SM00393
SUPFAM SSF82708
PROSITE PS51061
PS51673

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005737

cytoplasm

PMID:29581509[1]

ECO:0000314

C

ARPP21 localizes to the cytosol and overlaps staining with stress granule. ARPP21 used FLAG-tagg expression in HeLa cells and treated with arsenite Figure 2A,B

complete
CACAO 13231

acts_upstream_of_or_within

GO:0034605

cellular response to heat

PMID:18755693[2]

ECO:0000314

direct assay evidence used in manual assertion

P

occurs_in:(EMAPA:17838)

Seeded From UniProt

complete

enables

GO:0003674

molecular_function

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001374
InterPro:IPR036867

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:8869551[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005516

calmodulin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0112

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Rehfeld, F et al. (2018) The RNA-binding protein ARPP21 controls dendritic branching by functionally opposing the miRNA it hosts. Nat Commun 9 1235 PubMed GONUTS page
  2. Fujimoto, M et al. (2008) Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses. J. Biol. Chem. 283 29961-70 PubMed GONUTS page
  3. Ivkovic, S et al. (1996) ARPP-21: murine gene structure and promoter identification of a neuronal phosphoprotein enriched in the limbic striatum. Brain Res. 709 10-6 PubMed GONUTS page