MOUSE:APOC2

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Apoc2
Protein Name(s)	Apolipoprotein C-II Apo-CII ApoC-II Apolipoprotein C2
External Links
UniProt	Q05020
EMBL	Z15090 Z22216 Z22217 BC024697
CCDS	CCDS39801.1
PIR	S31799
RefSeq	NP_001264873.1
UniGene	Mm.28394
ProteinModelPortal	Q05020
SMR	Q05020
STRING	10090.ENSMUSP00000115173
PhosphoSite	Q05020
PaxDb	Q05020
PRIDE	Q05020
Ensembl	ENSMUST00000003074 ENSMUST00000134116 ENSMUST00000142352 ENSMUST00000150569
GeneID	11813
KEGG	mmu:11813
UCSC	uc009fmt.2
CTD	344
MGI	MGI:88054
eggNOG	NOG25045
HOGENOM	HOG000034002
HOVERGEN	HBG050548
InParanoid	Q05020
OMA	KIRDMYS
OrthoDB	EOG7TXKKM
PhylomeDB	Q05020
TreeFam	TF338218
Reactome	REACT_198569 REACT_213857 REACT_216017
NextBio	279691
PRO	PR:Q05020
Proteomes	UP000000589
Bgee	Q05020
CleanEx	MM_APOC2
ExpressionAtlas	Q05020
Genevestigator	Q05020
GO	GO:0042627 GO:0005829 GO:0005576 GO:0034364 GO:0034362 GO:0034361 GO:0008047 GO:0016042 GO:0006869 GO:0042953 GO:0042493
Gene3D	1.10.1440.10
InterPro	IPR008019 IPR023121
PANTHER	PTHR16566
Pfam	PF05355

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0060697	positive regulation of phospholipid catabolic process	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	P	Seeded From UniProt	complete
enables	GO:0060230	lipoprotein lipase activator activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	F	Seeded From UniProt	complete
involved_in	GO:0051006	positive regulation of lipoprotein lipase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	P	Seeded From UniProt	complete
enables	GO:0043274	phospholipase binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	F	Seeded From UniProt	complete
part_of	GO:0042627	chylomicron	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	C	Seeded From UniProt	complete
involved_in	GO:0034384	high-density lipoprotein particle clearance	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	P	Seeded From UniProt	complete
involved_in	GO:0034382	chylomicron remnant clearance	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	P	Seeded From UniProt	complete
part_of	GO:0034366	spherical high-density lipoprotein particle	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	C	Seeded From UniProt	complete
part_of	GO:0034363	intermediate-density lipoprotein particle	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	C	Seeded From UniProt	complete
part_of	GO:0034362	low-density lipoprotein particle	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	C	Seeded From UniProt	complete
part_of	GO:0034361	very-low-density lipoprotein particle	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	C	Seeded From UniProt	complete
enables	GO:0016004	phospholipase activator activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	F	Seeded From UniProt	complete
involved_in	GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	P	Seeded From UniProt	complete
involved_in	GO:0010518	positive regulation of phospholipase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	P	Seeded From UniProt	complete
enables	GO:0008289	lipid binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000421988 UniProtKB:P02655	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0070328	triglyceride homeostasis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060697	positive regulation of phospholipid catabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
enables	GO:0060230	lipoprotein lipase activator activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	F	Seeded From UniProt	complete
enables	GO:0055102	lipase inhibitor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051006	positive regulation of lipoprotein lipase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048261	negative regulation of receptor-mediated endocytosis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045833	negative regulation of lipid metabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045723	positive regulation of fatty acid biosynthetic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
enables	GO:0043274	phospholipase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042953	lipoprotein transport	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2135	P	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	F	Seeded From UniProt	complete
part_of	GO:0042627	chylomicron	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034384	high-density lipoprotein particle clearance	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034382	chylomicron remnant clearance	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
part_of	GO:0034366	spherical high-density lipoprotein particle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	C	Seeded From UniProt	complete
part_of	GO:0034363	intermediate-density lipoprotein particle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	C	Seeded From UniProt	complete
part_of	GO:0034362	low-density lipoprotein particle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	C	Seeded From UniProt	complete
part_of	GO:0034361	very-low-density lipoprotein particle	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0033700	phospholipid efflux	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0033344	cholesterol efflux	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032375	negative regulation of cholesterol transport	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
enables	GO:0016004	phospholipase activator activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010916	negative regulation of very-low-density lipoprotein particle clearance	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010898	positive regulation of triglyceride catabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010518	positive regulation of phospholipase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	P	Seeded From UniProt	complete
enables	GO:0008289	lipid binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	F	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P02655	C	Seeded From UniProt	complete
involved_in	GO:0043086	negative regulation of catalytic activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0055102	P	Seeded From UniProt	complete
involved_in	GO:0006629	lipid metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008019	P	Seeded From UniProt	complete
involved_in	GO:0006869	lipid transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008019	P	Seeded From UniProt	complete
enables	GO:0008047	enzyme activator activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008019	F	Seeded From UniProt	complete
part_of	GO:0042627	chylomicron	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008019	C	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-MMU-6784616 Reactome:R-MMU-2425403	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	Reactome:R-MMU-2425403	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0034362	low-density lipoprotein particle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0427	C	Seeded From UniProt	complete
part_of	GO:0034364	high-density lipoprotein particle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0345	C	Seeded From UniProt	complete
part_of	GO:0042627	chylomicron	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0162	C	Seeded From UniProt	complete
part_of	GO:0034361	very-low-density lipoprotein particle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0850	C	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C	Seeded From UniProt	complete
involved_in	GO:0006629	lipid metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0443	P	Seeded From UniProt	complete
involved_in	GO:0006869	lipid transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0445	P	Seeded From UniProt	complete
involved_in	GO:0016042	lipid catabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0442	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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MOUSE:APOC2

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