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MOUSE:AOFA
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Maoa | |
| Protein Name(s) | Amine oxidase [flavin-containing] A
Monoamine oxidase type A MAO-A | |
| External Links | ||
| UniProt | Q64133 | |
| EMBL | AL805907 AL831729 AL831729 AL805907 CH466584 BC029100 S78615 S78606 | |
| CCDS | CCDS30033.1 | |
| RefSeq | NP_776101.3 | |
| UniGene | Mm.21108 | |
| ProteinModelPortal | Q64133 | |
| SMR | Q64133 | |
| BioGrid | 201307 | |
| IntAct | Q64133 | |
| MINT | MINT-4997361 | |
| BindingDB | Q64133 | |
| ChEMBL | CHEMBL3681 | |
| PhosphoSite | Q64133 | |
| MaxQB | Q64133 | |
| PaxDb | Q64133 | |
| PRIDE | Q64133 | |
| Ensembl | ENSMUST00000026013 | |
| GeneID | 17161 | |
| KEGG | mmu:17161 | |
| UCSC | uc009ssa.2 | |
| CTD | 4128 | |
| MGI | MGI:96915 | |
| eggNOG | COG1231 | |
| GeneTree | ENSGT00730000110903 | |
| HOGENOM | HOG000221615 | |
| HOVERGEN | HBG004255 | |
| InParanoid | Q64133 | |
| KO | K00274 | |
| OMA | DAPWEAP | |
| OrthoDB | EOG7K6PTP | |
| TreeFam | TF313314 | |
| Reactome | REACT_230130 REACT_231054 REACT_234896 REACT_242222 REACT_257747 | |
| NextBio | 291438 | |
| PRO | PR:Q64133 | |
| Proteomes | UP000000589 | |
| Bgee | Q64133 | |
| CleanEx | MM_MAOA | |
| ExpressionAtlas | Q64133 | |
| Genevestigator | Q64133 | |
| GO | GO:0016021 GO:0005741 GO:0005739 GO:0008131 GO:0042420 GO:0042135 | |
| InterPro | IPR002937 IPR001613 | |
| Pfam | PF01593 | |
| PRINTS | PR00757 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0051378 |
serotonin binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61898 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050660 |
flavin adenine dinucleotide binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61898 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0042443 |
phenylethylamine metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61898 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0042428 |
serotonin metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61898 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0042420 |
dopamine catabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0009967 |
positive regulation of signal transduction |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008131 |
primary amine oxidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008131 |
primary amine oxidase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61898 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005741 |
mitochondrial outer membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:61898 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(EMAPA:16846)|part_of:(EMAPA:16894)|part_of:(EMAPA:17373)|part_of:(EMAPA:16105) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P21397 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q53YE7 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042135 |
neurotransmitter catabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006584 |
catecholamine metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005741 |
mitochondrial outer membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Jones, SR et al. (1998) Profound neuronal plasticity in response to inactivation of the dopamine transporter. Proc. Natl. Acad. Sci. U.S.A. 95 4029-34 PubMed GONUTS page
- ↑ Coatrieux, C et al. (2007) MAO-A-induced mitogenic signaling is mediated by reactive oxygen species, MMP-2, and the sphingolipid pathway. Free Radic. Biol. Med. 43 80-9 PubMed GONUTS page
- ↑ Kabayama, M et al. (2013) Rines E3 ubiquitin ligase regulates MAO-A levels and emotional responses. J. Neurosci. 33 12940-53 PubMed GONUTS page
- ↑ Pagliarini, DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 112-23 PubMed GONUTS page
- ↑ Mootha, VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115 629-40 PubMed GONUTS page
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