GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
MOUSE:AAKG2
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Prkag2 | |
| Protein Name(s) | 5'-AMP-activated protein kinase subunit gamma-2
AMPK gamma2 AMPK subunit gamma-2 | |
| External Links | ||
| UniProt | Q91WG5 | |
| EMBL | AY348864 AC116151 AC125270 BC015283 | |
| CCDS | CCDS19130.1 CCDS51437.1 | |
| RefSeq | NP_001164027.1 NP_663376.2 | |
| UniGene | Mm.33649 | |
| ProteinModelPortal | Q91WG5 | |
| SMR | Q91WG5 | |
| BioGrid | 223832 | |
| IntAct | Q91WG5 | |
| PhosphoSite | Q91WG5 | |
| MaxQB | Q91WG5 | |
| PaxDb | Q91WG5 | |
| PRIDE | Q91WG5 | |
| Ensembl | ENSMUST00000030784 ENSMUST00000114975 | |
| GeneID | 108099 | |
| KEGG | mmu:108099 | |
| UCSC | uc008wsk.2 | |
| CTD | 51422 | |
| MGI | MGI:1336153 | |
| eggNOG | COG0517 | |
| GeneTree | ENSGT00390000009849 | |
| HOGENOM | HOG000176880 | |
| HOVERGEN | HBG050431 | |
| InParanoid | Q91WG5 | |
| KO | K07200 | |
| OMA | XVQIYEL | |
| OrthoDB | EOG74FF0W | |
| TreeFam | TF313247 | |
| Reactome | REACT_199054 REACT_205688 REACT_220701 REACT_250379 REACT_257268 REACT_257725 | |
| ChiTaRS | Prkag2 | |
| NextBio | 360062 | |
| PRO | PR:Q91WG5 | |
| Proteomes | UP000000589 | |
| Bgee | Q91WG5 | |
| ExpressionAtlas | Q91WG5 | |
| Genevestigator | Q91WG5 | |
| GO | GO:0031588 GO:0005829 GO:0005615 GO:0043531 GO:0016208 GO:0004679 GO:0005524 GO:0004862 GO:0008603 GO:0008607 GO:0030295 GO:0006633 GO:0005977 GO:0035556 GO:0010800 GO:0019217 GO:0006110 | |
| InterPro | IPR000644 | |
| Pfam | PF00571 | |
| SMART | SM00116 | |
| PROSITE | PS51371 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
acts_upstream_of_or_within |
GO:0050790 |
regulation of catalytic activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:727782 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0045860 |
positive regulation of protein kinase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043531 |
ADP binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0035556 |
intracellular signal transduction |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031588 |
nucleotide-activated protein kinase complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031588 |
nucleotide-activated protein kinase complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:727782 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0030295 |
protein kinase activator activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019901 |
protein kinase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019901 |
protein kinase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:727782 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0019217 |
regulation of fatty acid metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016208 |
AMP binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:727782 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0010800 |
positive regulation of peptidyl-threonine phosphorylation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008607 |
phosphorylase kinase regulator activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008603 |
cAMP-dependent protein kinase regulator activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0006469 |
negative regulation of protein kinase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0006110 |
regulation of glycolytic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0005977 |
glycogen metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004862 |
cAMP-dependent protein kinase inhibitor activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
contributes_to |
GO:0004679 |
AMP-activated protein kinase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:727782 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004679 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004679 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006468 |
protein phosphorylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004679 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032147 |
activation of protein kinase activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0030295 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032147 |
activation of protein kinase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0030295 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0071901 |
negative regulation of protein serine/threonine kinase activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004862 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0071901 |
negative regulation of protein serine/threonine kinase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004862 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045860 |
positive regulation of protein kinase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0043531 |
ADP binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035556 |
intracellular signal transduction |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0031588 |
nucleotide-activated protein kinase complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0030295 |
protein kinase activator activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019901 |
protein kinase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019217 |
regulation of fatty acid metabolic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010800 |
positive regulation of peptidyl-threonine phosphorylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008607 |
phosphorylase kinase regulator activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008603 |
cAMP-dependent protein kinase regulator activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006469 |
negative regulation of protein kinase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006110 |
regulation of glycolytic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0005977 |
glycogen metabolic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004862 |
cAMP-dependent protein kinase inhibitor activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9UGJ0 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0050790 |
regulation of catalytic activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A0A140UHX4 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0031588 |
nucleotide-activated protein kinase complex |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A0A140UHX4 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019901 |
protein kinase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A0A140UHX4 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016208 |
AMP binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A0A140UHX4 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004679 |
AMP-activated protein kinase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:A0A140UHX4 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0032559 |
adenyl ribonucleotide binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071900 |
regulation of protein serine/threonine kinase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-MMU-1454711 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005654 |
nucleoplasm |
Reactome:R-MMU-1605475 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004679 |
AMP-activated protein kinase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006631 |
fatty acid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Turnley, AM et al. (1999) Cellular distribution and developmental expression of AMP-activated protein kinase isoforms in mouse central nervous system. J. Neurochem. 72 1707-16 PubMed GONUTS page
a
c
n
p
- GO:0008607 ! phosphorylase kinase regulator activity
- GO:0045860 ! positive regulation of protein kinase activity
- GO:0010800 ! positive regulation of peptidyl-threonine phosphorylation
- GO:0019901 ! protein kinase binding
- GO:0030295 ! protein kinase activator activity
- GO:0006468 ! protein phosphorylation
r
