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MICEC:Q8KNE0
Contents
Species (Taxon ID) | Micromonospora echinospora (Micromonospora purpurea). (1877) | |
Gene Name(s) | calG2 (ECO:0000313 with EMBL:AAM70348.1) | |
Protein Name(s) | CalG2 (ECO:0000313 with EMBL:AAM70348.1) | |
External Links | ||
UniProt | Q8KNE0 | |
EMBL | AF497482 | |
PDB | 3IAA 3RSC | |
PDBsum | 3IAA 3RSC | |
ProteinModelPortal | Q8KNE0 | |
CAZy | GT1 | |
EvolutionaryTrace | Q8KNE0 | |
GO | GO:0016758 GO:0016999 | |
InterPro | IPR002213 IPR006326 | |
PANTHER | PTHR11926 | |
Pfam | PF00201 | |
TIGRFAMs | TIGR01426 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0016757 |
transferase activity, transferring glycosyl groups |
ECO:0000314 |
F |
CalG2 is a glycosyltransferase from Micromonospora echinospora derived from the calicheamicin gene cluster. Structure of CalG2 was solved by X-ray crystallography. Fig 2 & 3 show the structure with bound substrate and the catalytic residues. |
complete | |||||
GO:0016757 |
transferase activity, transferring glycosyl groups |
ECO:0000314 |
F |
CalG2 is a glycosyltransferase from the calicheamicin gene cluster in the organism, Micromonospora echinospora.Function was characterized by HPLC (High Pressure Liquid Chromatography) and Mass spectrometry as shown in Fig 5. |
complete | |||||
enables |
GO:0016758 |
transferase activity, transferring hexosyl groups |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016999 |
antibiotic metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Chang, A et al. (2011) Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity. Proc. Natl. Acad. Sci. U.S.A. 108 17649-54 PubMed GONUTS page
- ↑ Zhang, C et al. (2008) Biochemical and structural insights of the early glycosylation steps in calicheamicin biosynthesis. Chem. Biol. 15 842-53 PubMed GONUTS page