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METFE:G3P

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Species (Taxon ID) Methanothermus fervidus. (2180)
Gene Name(s) gap
Protein Name(s) Glyceraldehyde-3-phosphate dehydrogenase

GAPDH NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase

External Links
UniProt P10618
EMBL M19980
PIR JT0286
RefSeq YP_004003841.1
PDB 1CF2
PDBsum 1CF2
ProteinModelPortal P10618
SMR P10618
GeneID 9961991
KEGG mfv:Mfer_0276
KO K00150
SABIO-RK P10618
UniPathway UPA00109
EvolutionaryTrace P10618
GO GO:0005737
GO:0043891
GO:0004365
GO:0047100
GO:0051287
GO:0050661
GO:0006096
Gene3D 3.40.50.720
HAMAP MF_00559
InterPro IPR020831
IPR020830
IPR020829
IPR020828
IPR006436
IPR016040
Pfam PF02800
PF00044
PIRSF PIRSF000149
SMART SM00846
TIGRFAMs TIGR01546
PROSITE PS00071

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0047100

glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity

PMID:10491162[1]

ECO:0000315

F

Table 2 depicts kinetic parameters of both the wild-type and mutant M. fervidus GraP-DHs.

complete
CACAO 7750

enables

GO:0047100

glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity

PMID:10491162[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006436

C

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006436

P

Seeded From UniProt

complete

enables

GO:0008839

4-hydroxy-tetrahydrodipicolinate reductase

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000846

F

Seeded From UniProt

complete

involved_in

GO:0009089

lysine biosynthetic process via diaminopimelate

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000846

P

Seeded From UniProt

complete

enables

GO:0016620

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006436
InterPro:IPR020828
InterPro:IPR020829
InterPro:IPR020830
InterPro:IPR020831

F

Seeded From UniProt

complete

enables

GO:0050661

NADP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006436

F

Seeded From UniProt

complete

enables

GO:0051287

NAD binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006436

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000846
InterPro:IPR006436
InterPro:IPR020828
InterPro:IPR020829
InterPro:IPR020830
InterPro:IPR020831

P

Seeded From UniProt

complete

enables

GO:0043891

glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.2.1.59

F

Seeded From UniProt

complete

enables

GO:0004365

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101650

F

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101650

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000101650

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0006096

glycolytic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0324
UniPathway:UPA00109

P

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Talfournier, F et al. (1999) Functional characterization of the phosphorylating D-glyceraldehyde 3-phosphate dehydrogenase from the archaeon Methanothermus fervidus by comparative molecular modelling and site-directed mutagenesis. Eur. J. Biochem. 265 93-104 PubMed GONUTS page