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LISMN:Q6E8U6

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Species (Taxon ID) Listeria monocytogenes. (1639)
Gene Name(s) hly (ECO:0000313 with EMBL:AAS85364.1)
Protein Name(s) Hly (ECO:0000313 with EMBL:AAS85364.1)

Listeriolysin O (ECO:0000313 with EMBL:ABH07633.1)

External Links
UniProt Q6E8U6
EMBL AY512412
AY512494
DQ838562
FJ030504
FJ030527
FJ030568
FJ030575
FJ030587
FJ030602
FJ030610
HE999704
RefSeq WP_015454006.1
YP_007602418.1
ProteinModelPortal Q6E8U6
EnsemblBacteria CCQ19504
GeneID 14824605
KEGG lmoe:BN418_0212
KO K11031
Proteomes UP000011106
GO GO:0015485
GO:0009405
Gene3D 3.90.840.10
InterPro IPR001869
Pfam PF01289
PRINTS PR01400
SUPFAM SSF56978
PROSITE PS00481

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009405

pathogenesis

PMID:19472336[1]

ECO:0000314

P

Figure 4. Sheep erythrocytes treated with both known immunotoxin and suspected cytotoxic LLC to compare effects on cell death

complete
CACAO 9121

involved_in

GO:0009405

pathogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001869
InterPro:IPR036359
InterPro:IPR036363

P

Seeded From UniProt

complete

enables

GO:0015485

cholesterol binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001869
InterPro:IPR036359
InterPro:IPR036363

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

involved_in

GO:0044179

hemolysis in other organism

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0354

P

Seeded From UniProt

complete

part_of

GO:0020002

host cell plasma membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-1032

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0008289

lipid binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0446

F

Seeded From UniProt

complete

involved_in

GO:0019835

cytolysis

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0204

P

Seeded From UniProt

complete

part_of

GO:0033644

host cell membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-1043

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

part_of

GO:0020002

host cell plasma membrane

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0375

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Bergelt, S et al. (2009) Listeriolysin O as cytotoxic component of an immunotoxin. Protein Sci. 18 1210-20 PubMed GONUTS page