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LISM4:A0A0H3GD84

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Species (Taxon ID) Listeria monocytogenes serotype 1/2a (strain 10403S). (393133)
Gene Name(s) No Information Provided.
Protein Name(s) Listeriolysin O (ECO:0000313 with EMBL:AEO05213.1)
External Links
UniProt A0A0H3GD84
EMBL CP002002
RefSeq WP_003722731.1
PDB 4CDB
PDBsum 4CDB
ProteinModelPortal A0A0H3GD84
SMR A0A0H3GD84
EnsemblBacteria AEO05213
KEGG lmt:LMRG_02624
KO K11031
OMA LTYNNQE
Proteomes UP000001288
GO GO:0015485
GO:0009405
Gene3D 3.90.840.10
InterPro IPR001869
Pfam PF01289
PRINTS PR01400
SUPFAM SSF56978
PROSITE PS00481

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009405

pathogenesis

PMID:10639481[1]

ECO:0000315

P

Figure 3. shows that LLO-negative bacteria are trapped in the host's vacuoles, unable to complete cell-to-cell spread.

complete
CACAO 5245

GO:0030682

evasion or tolerance of host defense response

PMID:9864207[2]

ECO:0000314

P

Figure 7. Listeriolysin O in Listeria monocytogenes 10403S (belongs to serotype 1) Experimental results determined the differences in expression of Listeriolysin O between Listeria monocytogenes growth in vitro and in the mammalian cell cytosol.

complete
CACAO 12431

involved_in

GO:0009405

pathogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001869
InterPro:IPR036359
InterPro:IPR036363

P

Seeded From UniProt

complete

enables

GO:0015485

cholesterol binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001869
InterPro:IPR036359
InterPro:IPR036363

F

Seeded From UniProt

complete

part_of

GO:0033644

host cell membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-1043

C

Seeded From UniProt

complete

involved_in

GO:0019835

cytolysis

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0204

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0044179

hemolysis in other organism

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0354

P

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

enables

GO:0008289

lipid binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0446

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0020002

host cell plasma membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-1032

C

Seeded From UniProt

complete

part_of

GO:0020002

host cell plasma membrane

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0375

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Gedde, MM et al. (2000) Role of listeriolysin O in cell-to-cell spread of Listeria monocytogenes. Infect. Immun. 68 999-1003 PubMed GONUTS page
  2. Moors, MA et al. (1999) Expression of listeriolysin O and ActA by intracellular and extracellular Listeria monocytogenes. Infect. Immun. 67 131-9 PubMed GONUTS page