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LEPIR:C0J1Q3

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Species (Taxon ID) Leptospira interrogans. (173)
Gene Name(s) ligB (ECO:0000313 with EMBL:ACH98095.1)
Protein Name(s) LigB (ECO:0000313 with EMBL:ACH98095.1)
External Links
UniProt C0J1Q3
EMBL EU700268
STRING 189518.LA3778
InterPro IPR003343
IPR008964
Pfam PF02368
SMART SM00635
SUPFAM SSF49373

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0045916

negative regulation of complement activation

PMID:22911815[1]

ECO:0000314

P

Figure 3 shows the inhibition of both the alternative and classical pathways of complement activation through the inhibition of complement-mediated hemolysis of rabbit erthrocytes.

complete
CACAO 7551

involved_in

GO:0045916

negative regulation of complement activation

PMID:22911815[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Choy, HA (2012) Multiple activities of LigB potentiate virulence of Leptospira interrogans: inhibition of alternative and classical pathways of complement. PLoS ONE 7 e41566 PubMed GONUTS page