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LEPIR:A0A0C5XAD8

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Species (Taxon ID) Leptospira interrogans serovar Linhai str. 56609. (1395589)
Gene Name(s) mazF (ECO:0000313 with EMBL:AJR16585.1)
Protein Name(s) mRNA interferase (ECO:0000256 with PIRNR:PIRNR033490)
External Links
UniProt A0A0C5XAD8
EMBL CP006725
RefSeq WP_000237066.1
EnsemblBacteria AJR16585
KEGG lis:LIL_30046
PATRIC fig|1395589.3.peg.4688
KO K07171
OrthoDB 1754531at2
Proteomes UP000032263
GO GO:0003677
GO:0004519
Gene3D 2.30.30.110
InterPro IPR003477
IPR011067
PANTHER PTHR33988
Pfam PF02452
PIRSF PIRSF033490

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004519

P

Seeded From UniProt

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004518

P

Seeded From UniProt

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003477

F

Seeded From UniProt

enables

GO:0004519

endonuclease activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0255

F

Seeded From UniProt

enables

GO:0016787

hydrolase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

enables

GO:0004518

nuclease activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004519

P

Seeded From UniProt

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004518

P

Seeded From UniProt

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003477

F

Seeded From UniProt

enables

GO:0004519

endonuclease activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0255

F

Seeded From UniProt

enables

GO:0016787

hydrolase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

enables

GO:0004518

nuclease activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

GO:0110001

toxin-antitoxin complex

PMID:25461800[1]

ECO:0001258

C

Figure 1.B shows that MazF, a protein from Leptospira interrogans, kills the cell when produced alone, but complexes with MazE to repress itself.

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Komi, KK et al. (2015) ChpK and MazF of the toxin-antitoxin modules are involved in the virulence of Leptospira interrogans during infection. Microbes Infect. 17 34-47 PubMed GONUTS page