LEPIN:G1UB28

Species (Taxon ID)	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai(strain 56601). (189518)
Gene Name(s)	No Information Provided.
Protein Name(s)	mRNA interferase (ECO:0000256 with PIRNR:PIRNR033490)
External Links
UniProt	G1UB28
EMBL	AE010300
RefSeq	NP_713024.1 WP_000617906.1
ProteinModelPortal	G1UB28
STRING	189518.LA_2843
EnsemblBacteria	AAN50042
GeneID	1152186
KEGG	lil:LA_2843
eggNOG	ENOG41081UW COG2337
InParanoid	G1UB28
KO	K07171
OMA	FNHSRIT
BioCyc	LINT189518:G1GL4-2296-MONOMER
Proteomes	UP000001408
GO	GO:0003677 GO:0004519
Gene3D	2.30.30.110
InterPro	IPR003477 IPR011067
PANTHER	PTHR33988
Pfam	PF02452
PIRSF	PIRSF033490

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004519	P		Seeded From UniProt
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004518	P		Seeded From UniProt
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003477	F		Seeded From UniProt
enables	GO:0016787	hydrolase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt
enables	GO:0004519	endonuclease activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0255	F		Seeded From UniProt
enables	GO:0004518	nuclease activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0540	F		Seeded From UniProt
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004519	P		Seeded From UniProt
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004518	P		Seeded From UniProt
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003477	F		Seeded From UniProt
enables	GO:0016787	hydrolase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt
enables	GO:0004519	endonuclease activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0255	F		Seeded From UniProt
	GO:0004540	ribonuclease activity	PMID:25461800	ECO:0005653			F		Fig. 5 shows that mazF (a toxin) found in Leptospira interrogans degrades RNA.	complete CACAO 13616
enables	GO:0004518	nuclease activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0540	F		Seeded From UniProt
	GO:0001907	killing by symbiont of host cells	PMID:25461800	ECO:0005034			P		Fig. 3 shows that MazF (aka LA_2843) from Leptospira interrogans is involved in inducing necrotic death of the THP-1 host cell.	complete CACAO 13640
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References

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