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LEPBJ:Q04VF3

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Species (Taxon ID) Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197). (355277)
Gene Name(s) mazE (ECO:0000313 with EMBL:ABJ75117.1)
Protein Name(s) Proteic killer gene system protein, suppressor of inhibitory function of MazF (ECO:0000313 with EMBL:ABJ75117.1)
External Links
UniProt Q04VF3
EMBL CP000350
RefSeq WP_011670966.1
ProteinModelPortal Q04VF3
EnsemblBacteria ABJ75117
GeneID 4407227
KEGG lbj:LBJ_0401
HOGENOM HOG000133721
KO K07172
OMA DKDEWEW
BioCyc LBOR355277:G1G6G-475-MONOMER
Proteomes UP000000656
GO GO:0003677
InterPro IPR007159
IPR037914
Pfam PF04014
SMART SM00966
SUPFAM SSF89447

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007159

F

Seeded From UniProt

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007159

F

Seeded From UniProt

GO:0008284

positive regulation of cell population proliferation

PMID:25461800[1]

ECO:0001258

P

Fig. 1B shows that mazE (an anti-toxin) rescues the expression of cells expressing only the mazF toxin in Leptospira interrogans.

complete
CACAO 13591

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Komi, KK et al. (2015) ChpK and MazF of the toxin-antitoxin modules are involved in the virulence of Leptospira interrogans during infection. Microbes Infect. 17 34-47 PubMed GONUTS page