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LAMBD:RCRO
Contents
| Species (Taxon ID) | Escherichia phage lambda (Bacteriophage lambda). (10710) | |
| Gene Name(s) | cro | |
| Protein Name(s) | Regulatory protein cro | |
| External Links | ||
| UniProt | P03040 | |
| EMBL | J02459 | |
| PIR | B94614 | |
| RefSeq | NP_040629.1 | |
| PDB | 1COP 1D1L 1D1M 1ORC 2A63 2ECS 2ORC 2OVG 3ORC 4CRO 5CRO 6CRO | |
| PDBsum | 1COP 1D1L 1D1M 1ORC 2A63 2ECS 2ORC 2OVG 3ORC 4CRO 5CRO 6CRO | |
| DisProt | DP00741 | |
| ProteinModelPortal | P03040 | |
| SMR | P03040 | |
| IntAct | P03040 | |
| MINT | MINT-121263 | |
| GeneID | 2703491 | |
| KEGG | vg:2703467 | |
| OrthoDB | VOG090001UA | |
| EvolutionaryTrace | P03040 | |
| Proteomes | UP000001711 | |
| GO | GO:0003677 GO:0006355 GO:0006351 | |
| Gene3D | 3.30.240.10 | |
| InterPro | IPR000655 IPR010982 | |
| Pfam | PF09048 | |
| PIRSF | PIRSF003217 | |
| PRINTS | PR00030 | |
| ProDom | PD054632 | |
| SUPFAM | SSF47413 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0098689 |
latency-replication decision |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032897 |
negative regulation of viral transcription |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0032897 |
negative regulation of viral transcription |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_regulation_target:(UniProtKB:P03034) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010944 |
negative regulation of transcription by competitive promoter binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009411 |
response to UV |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019046 |
release from viral latency |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
happens_during:(GO:0009411) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0001047 |
core promoter binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019042 |
viral latency |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0098689 |
latency-replication decision |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lee, S et al. (2018) The Developmental Switch in Bacteriophage λ: A Critical Role of the Cro Protein. J. Mol. Biol. 430 58-68 PubMed GONUTS page
- ↑ Folkmanis, A et al. (1976) Purification and properties of a DNA-binding protein with characteristics expected for the Cro protein of bacteriophage lambda, a repressor essential for lytic growth. Proc. Natl. Acad. Sci. U.S.A. 73 2249-53 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Schubert, RA et al. (2007) Cro's role in the CI Cro bistable switch is critical for {lambda}'s transition from lysogeny to lytic development. Genes Dev. 21 2461-72 PubMed GONUTS page
- ↑ 4.0 4.1 Albright, RA & Matthews, BW (1998) Crystal structure of lambda-Cro bound to a consensus operator at 3.0 A resolution. J. Mol. Biol. 280 137-51 PubMed GONUTS page
- ↑ Matsuo, H et al. (1995) Three-dimensional dimer structure of the lambda-Cro repressor in solution as determined by heteronuclear multidimensional NMR. J. Mol. Biol. 254 668-80 PubMed GONUTS page
