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LACLM:A2RK88
Contents
Species (Taxon ID) | Lactococcus lactis subsp. cremoris (strain MG1363). (416870) | |
Gene Name(s) | No Information Provided. | |
Protein Name(s) | Drug-export protein (ECO:0000313 with EMBL:CAL97698.1) | |
External Links | ||
UniProt | A2RK88 | |
EMBL | AM406671 | |
RefSeq | WP_011835012.1 YP_001032418.1 | |
ProteinModelPortal | A2RK88 | |
STRING | 416870.llmg_1104 | |
EnsemblBacteria | CAL97698 | |
GeneID | 4798113 | |
KEGG | llm:llmg_1104 | |
PATRIC | 22283356 | |
eggNOG | COG0477 | |
HOGENOM | HOG000239123 | |
OMA | NFAMLLF | |
OrthoDB | EOG66MQRH | |
BioCyc | LLAC416870:GCDT-1130-MONOMER | |
Proteomes | UP000000364 | |
GO | GO:0016021 GO:0055085 | |
InterPro | IPR011701 IPR020846 IPR001411 | |
Pfam | PF07690 | |
PRINTS | PR01036 | |
SUPFAM | SSF103473 | |
PROSITE | PS50850 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0015299 |
solute:proton antiporter activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Table 2 shows that expression of the cmbT gene in the CT501 strain confers resistance to a range of antibiotics. Figure 3A shows the decreased intercalation of ethidium bromide into DNA (less fluorescence) in the CT501 strain. Figure 3B shows that this does not change in the presence of an ATPase inhibitor, implying the transport of ethidium bromide out of the cell is proton motive force driven. |
complete | ||||
enables |
GO:0015299 |
solute:proton antiporter activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046618 |
drug export |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015307 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0055085 |
transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Filipic, B et al. (2013) The cmbT gene encodes a novel major facilitator multidrug resistance transporter in Lactococcus lactis. Res. Microbiol. 164 46-54 PubMed GONUTS page