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LACLM:A2RK88

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Species (Taxon ID) Lactococcus lactis subsp. cremoris (strain MG1363). (416870)
Gene Name(s) No Information Provided.
Protein Name(s) Drug-export protein (ECO:0000313 with EMBL:CAL97698.1)
External Links
UniProt A2RK88
EMBL AM406671
RefSeq WP_011835012.1
YP_001032418.1
ProteinModelPortal A2RK88
STRING 416870.llmg_1104
EnsemblBacteria CAL97698
GeneID 4798113
KEGG llm:llmg_1104
PATRIC 22283356
eggNOG COG0477
HOGENOM HOG000239123
OMA NFAMLLF
OrthoDB EOG66MQRH
BioCyc LLAC416870:GCDT-1130-MONOMER
Proteomes UP000000364
GO GO:0016021
GO:0055085
InterPro IPR011701
IPR020846
IPR001411
Pfam PF07690
PRINTS PR01036
SUPFAM SSF103473
PROSITE PS50850

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0015299

solute:proton antiporter activity

PMID:22985829[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Table 2 shows that expression of the cmbT gene in the CT501 strain confers resistance to a range of antibiotics. Figure 3A shows the decreased intercalation of ethidium bromide into DNA (less fluorescence) in the CT501 strain. Figure 3B shows that this does not change in the presence of an ATPase inhibitor, implying the transport of ethidium bromide out of the cell is proton motive force driven.

complete
CACAO 10719

enables

GO:0015299

solute:proton antiporter activity

PMID:22985829[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0046618

drug export

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0015307

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011701

C

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011701

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Filipic, B et al. (2013) The cmbT gene encodes a novel major facilitator multidrug resistance transporter in Lactococcus lactis. Res. Microbiol. 164 46-54 PubMed GONUTS page