LACLM:6PGD

Species (Taxon ID)	Lactococcus lactis subsp. cremoris (strain MG1363). (416870)
Gene Name(s)	gnd
Protein Name(s)	6-phosphogluconate dehydrogenase, decarboxylating
External Links
UniProt	P96789
EMBL	U74322 AM406671
RefSeq	YP_001031931.1
PDB	2IYO 2IYP 2IZ0 2IZ1
PDBsum	2IYO 2IYP 2IZ0 2IZ1
ProteinModelPortal	P96789
SMR	P96789
STRING	416870.llmg_0586
EnsemblBacteria	CAL97186
GeneID	4798708
KEGG	llm:llmg_0586
PATRIC	22282257
eggNOG	COG0362
HOGENOM	HOG000255147
KO	K00033
OMA	SDEYNWD
OrthoDB	EOG6MSS4W
BioCyc	LLAC416870:GCDT-613-MONOMER
SABIO-RK	P96789
UniPathway	UPA00115
EvolutionaryTrace	P96789
Proteomes	UP000000364
GO	GO:0050661 GO:0004616 GO:0019521 GO:0006098
Gene3D	1.10.1040.10 1.20.5.320 3.40.50.720
InterPro	IPR008927 IPR006114 IPR006113 IPR006115 IPR006184 IPR013328 IPR012284 IPR016040
Pfam	PF00393 PF03446
PIRSF	PIRSF000109
SUPFAM	SSF48179
TIGRFAMs	TIGR00873
PROSITE	PS00461

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0006525	arginine metabolic process	PMID:9931298	ECO:0000315			P		As shown on page 57, "The role of the L. lactis 6-PGDH Arg-447 in binding of substrate" paragraph of the associated PMID:"Despite the fact that the mutated [6-PGDH] enzymes were all soluble... none had any activity whatsoever... confirming that this [Arginine] residue plays a critical role in activity."	complete CACAO 9641
enables	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006113 InterPro:IPR006114 InterPro:IPR006183 InterPro:IPR006184	F		Seeded From UniProt	complete
involved_in	GO:0006098	pentose-phosphate shunt	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006113 InterPro:IPR006114 InterPro:IPR006184	P		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR013328	F		Seeded From UniProt	complete
enables	GO:0050661	NADP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006115	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006113 InterPro:IPR006114 InterPro:IPR006183 InterPro:IPR006184 InterPro:IPR008927 InterPro:IPR013328	P		Seeded From UniProt	complete
enables	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.1.1.44	F		Seeded From UniProt	complete
involved_in	GO:0006098	pentose-phosphate shunt	GO_REF:0000037 GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0570 UniPathway:UPA00115	P		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
involved_in	GO:0019521	D-gluconate metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0311	P		Seeded From UniProt	complete
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References

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