LACC3:Q03BE6

Species (Taxon ID)	Lactobacillus casei (strain ATCC 334). (321967)
Gene Name(s)	ldh (ECO:0000256 with HAMAP-Rule:MF_00488)
Protein Name(s)	L-lactate dehydrogenase (ECO:0000256 with HAMAP-Rule:MF_00488) L-LDH (ECO:0000256 with HAMAP-Rule:MF_00488)
External Links
UniProt	Q03BE6
EMBL	CP000423
RefSeq	YP_805918.1
ProteinModelPortal	Q03BE6
STRING	321967.LSEI_0634
EnsemblBacteria	ABJ69476
GeneID	4419186
KEGG	lca:LSEI_0634
PATRIC	22204950
eggNOG	COG0039
HOGENOM	HOG000213793
KO	K00016
OMA	NIVLDEW
OrthoDB	EOG6091FG
BioCyc	LCAS321967:GH4S-633-MONOMER
Proteomes	UP000001651
GO	GO:0005737 GO:0004459 GO:0044262 GO:0006096
Gene3D	3.40.50.720 3.90.110.10
HAMAP	MF_00488
InterPro	IPR001557 IPR011304 IPR018177 IPR022383 IPR001236 IPR015955 IPR016040
PANTHER	PTHR11540
Pfam	PF02866 PF00056
PIRSF	PIRSF000102
PRINTS	PR00086
SUPFAM	SSF56327
TIGRFAMs	TIGR01771
PROSITE	PS00064

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0004459	L-lactate dehydrogenase activity	PMID:18231816	ECO:0000315			F		Figure 2 shows ldh zymogram assays of diffrent strains of L. casei. The deletion of ldh1 leads to the increase in ldh activity in the absence of D-lactate and in the presence of L-lactate. This activity is independent of the deletion of hicD, ldh2, ldh3 and ldh4.	complete CACAO 4526
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015955	F		Seeded From UniProt	complete
enables	GO:0004459	L-lactate dehydrogenase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011304 InterPro:IPR018177	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011304	C		Seeded From UniProt	complete
involved_in	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR015955	P		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001236	F		Seeded From UniProt	complete
enables	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001557 InterPro:IPR015955 InterPro:IPR022383	F		Seeded From UniProt	complete
involved_in	GO:0019752	carboxylic acid metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001557	P		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001236 InterPro:IPR001557 InterPro:IPR011304 InterPro:IPR015955 InterPro:IPR018177 InterPro:IPR022383	P		Seeded From UniProt	complete
enables	GO:0004459	L-lactate dehydrogenase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:1.1.1.27	F		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
involved_in	GO:0008152	metabolic process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0021	P		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0021	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
involved_in	GO:0006096	glycolytic process	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000103159	P		Seeded From UniProt	complete
enables	GO:0004459	L-lactate dehydrogenase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000103159	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000103159	C		Seeded From UniProt	complete
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