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KLEPN:NTRC

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Species (Taxon ID) Klebsiella pneumoniae. (573)
Gene Name(s) ntrC
Protein Name(s) Nitrogen assimilation regulatory protein
External Links
UniProt P03029
EMBL X02617
PIR B91060
ProteinModelPortal P03029
SMR P03029
GO GO:0005524
GO:0000156
GO:0043565
GO:0009399
GO:0006808
GO:0006355
GO:0006351
Gene3D 1.10.10.60
3.40.50.300
InterPro IPR003593
IPR011006
IPR009057
IPR002197
IPR027417
IPR010114
IPR001789
IPR002078
IPR025662
IPR025943
IPR025944
Pfam PF02954
PF00072
PF00158
PRINTS PR01590
SMART SM00382
SM00448
SUPFAM SSF46689
SSF52172
SSF52540
TIGRFAMs TIGR01818
PROSITE PS50110
PS00675
PS00676
PS00688
PS50045

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006355

regulation of transcription, DNA-templated

PMID:2041769[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000156

phosphorelay response regulator activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010114

F

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001789
InterPro:IPR010114

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009057
InterPro:IPR010114

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002078
InterPro:IPR010114

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002078

P

Seeded From UniProt

complete

involved_in

GO:0006808

regulation of nitrogen utilization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010114

P

Seeded From UniProt

complete

enables

GO:0008134

transcription factor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002078

F

Seeded From UniProt

complete

GO:0006355

regulation of transcription, DNA-dependent

PMID:2041769[1]

ECO:0000315

P

Figure 4: NTRC often prohibits transcriptional activation at promoters that need o54. Both the wild-type NTRC-phosphate and the mutant phenotype yielded the protection of -25, -24, and -13 guanine residues; these resides may be necessary for Eo54 recognition. However, -8 and -9 may be responsible for open promoter complexes, and the mutant phenotype is unable to express high levels of -8 and -9, causing the promoter to remain in closed form.

complete
CACAO 2719

enables

GO:0043565

sequence-specific DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002197

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0009399

nitrogen fixation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0535

P

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0902

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Austin, S et al. (1991) Influence of a mutation in the putative nucleotide binding site of the nitrogen regulatory protein NTRC on its positive control function. Nucleic Acids Res. 19 2281-7 PubMed GONUTS page