I34A1:PB1F2

Species (Taxon ID)	Influenza A virus (strain A/Puerto Rico/8/1934 H1N1). (211044)
Gene Name(s)	PB1
Protein Name(s)	Protein PB1-F2
External Links
UniProt	P0C0U1
EMBL	J02151 EF467819 CY009450
RefSeq	YP_418248.1
PDB	2HN8 3BUY
PDBsum	2HN8 3BUY
ProteinModelPortal	P0C0U1
SMR	P0C0U1
GeneID	3802042
Reactome	REACT_6213 REACT_9491
EvolutionaryTrace	P0C0U1
Proteomes	UP000009255
GO	GO:0005829 GO:0044164 GO:0044192 GO:0042025 GO:0016020 GO:0005758 GO:0046732 GO:0006915 GO:0039526 GO:0019048 GO:0035548 GO:0039545 GO:0019058 GO:0016032 GO:0019083
InterPro	IPR021045
Pfam	PF11986

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0035548	negative regulation of interferon-beta secretion	PMID:2195805	ECO:0000315			P		Fig 2 and 4. Protein PB1-F2 adversely affects IFN-β release.	complete CACAO 2129
involved_in	GO:0035548	negative regulation of interferon-beta secretion	PMID:2195805	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0039545	suppression by virus of host MAVS activity	PMID:21695240	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000523819	C		Seeded From UniProt	complete
part_of	GO:0044164	host cell cytosol	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000523819	C		Seeded From UniProt	complete
involved_in	GO:0046732	active induction of host immune response by virus	Reactome:R-HSA-168878	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-HSA-192704	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005758	mitochondrial intermembrane space	Reactome:R-HSA-168878	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0039545	suppression by virus of host MAVS activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1097	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0033650	host cell mitochondrion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1045	C		Seeded From UniProt	complete
involved_in	GO:0039526	modulation by virus of host apoptotic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1119	P		Seeded From UniProt	complete
part_of	GO:0044192	host cell mitochondrial inner membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1046 UniProtKB-SubCell:SL-0409	C		Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P		Seeded From UniProt	complete
part_of	GO:0030430	host cell cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1035	C		Seeded From UniProt	complete
involved_in	GO:0030683	evasion or tolerance by virus of host immune response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0899	P		Seeded From UniProt	complete
part_of	GO:0033644	host cell membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1043	C		Seeded From UniProt	complete
part_of	GO:0042025	host cell nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1048 UniProtKB-SubCell:SL-0414	C		Seeded From UniProt	complete
involved_in	GO:0039503	suppression by virus of host innate immune response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1090	P		Seeded From UniProt	complete
part_of	GO:0044164	host cell cytosol	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0384	C		Seeded From UniProt	complete
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References

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