HV1BR:ENV

Species (Taxon ID)	Human immunodeficiency virus type 1 group M subtype B (isolateBRU/LAI) (HIV-1). (11686)
Gene Name(s)	env
Protein Name(s)	Envelope glycoprotein gp160 Env polyprotein Surface protein gp120 SU Glycoprotein 120 gp120 Transmembrane protein gp41 TM Glycoprotein 41 gp41
External Links
UniProt	P03377
EMBL	K02013 A04321 M19921
PIR	A03975
PDB	1ENV 1ERF 1FAV 1P5A 1U6U 1U6V 2ZZO 3G9R 3MNW 3VGX 3VTP
PDBsum	1ENV 1ERF 1FAV 1P5A 1U6U 1U6V 2ZZO 3G9R 3MNW 3VGX 3VTP
ProteinModelPortal	P03377
SMR	P03377
BindingDB	P03377
ChEMBL	CHEMBL5826
EvolutionaryTrace	P03377
Proteomes	UP000007692
GO	GO:0044175 GO:0020002 GO:0016021 GO:0019031 GO:0055036 GO:0005198 GO:0006915 GO:0075512 GO:0030683 GO:0039654 GO:0019062
Gene3D	2.170.40.20
InterPro	IPR000777 IPR000328
Pfam	PF00516 PF00517
SUPFAM	SSF56502

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0005198	structural molecule activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000328	F		Seeded From UniProt	complete
part_of	GO:0019031	viral envelope	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000777 InterPro:IPR036377	C		Seeded From UniProt	complete
part_of	GO:0044175	host cell endosome membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	C		Seeded From UniProt	complete
involved_in	GO:0030683	evasion or tolerance by virus of host immune response	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	P		Seeded From UniProt	complete
involved_in	GO:1903905	positive regulation of establishment of T cell polarity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	P		Seeded From UniProt	complete
involved_in	GO:0019064	fusion of virus membrane with host plasma membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	P		Seeded From UniProt	complete
involved_in	GO:0039654	fusion of virus membrane with host endosome membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	P		Seeded From UniProt	complete
involved_in	GO:0019062	virion attachment to host cell	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	P		Seeded From UniProt	complete
involved_in	GO:0075512	clathrin-dependent endocytosis of virus by host cell	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	P		Seeded From UniProt	complete
part_of	GO:0019012	virion	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	C		Seeded From UniProt	complete
involved_in	GO:0090527	actin filament reorganization	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	P		Seeded From UniProt	complete
involved_in	GO:1903908	positive regulation of plasma membrane raft polarization	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	P		Seeded From UniProt	complete
involved_in	GO:0019082	viral protein processing	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	P		Seeded From UniProt	complete
part_of	GO:0020002	host cell plasma membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	C		Seeded From UniProt	complete
enables	GO:0005198	structural molecule activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	C		Seeded From UniProt	complete
part_of	GO:0055036	virion membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	C		Seeded From UniProt	complete
involved_in	GO:1903911	positive regulation of receptor clustering	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000613575	P		Seeded From UniProt	complete
part_of	GO:0019012	virion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04578:PRO_0000038427	C		Seeded From UniProt	complete
involved_in	GO:0075512	clathrin-dependent endocytosis of virus by host cell	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04578:PRO_0000038427	P		Seeded From UniProt	complete
involved_in	GO:0019062	virion attachment to host cell	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04578:PRO_0000038427	P		Seeded From UniProt	complete
part_of	GO:0020002	host cell plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04578:PRO_0000038427	C		Seeded From UniProt	complete
part_of	GO:0019012	virion	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04578:PRO_0000038428	C		Seeded From UniProt	complete
involved_in	GO:0019064	fusion of virus membrane with host plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04578:PRO_0000038428	P		Seeded From UniProt	complete
involved_in	GO:0075512	clathrin-dependent endocytosis of virus by host cell	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04578:PRO_0000038428	P		Seeded From UniProt	complete
involved_in	GO:0019082	viral protein processing	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P04578:PRO_0000239240	P		Seeded From UniProt	complete
involved_in	GO:0002223	stimulatory C-type lectin receptor signaling pathway	Reactome:R-HSA-5621481	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019062	virion attachment to host cell	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1161	P		Seeded From UniProt	complete
part_of	GO:0020002	host cell plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1032 UniProtKB-SubCell:SL-0375	C		Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P		Seeded From UniProt	complete
involved_in	GO:0030683	evasion or tolerance by virus of host immune response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0899	P		Seeded From UniProt	complete
part_of	GO:0019031	viral envelope	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0261	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0033644	host cell membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1043	C		Seeded From UniProt	complete
involved_in	GO:0075512	clathrin-dependent endocytosis of virus by host cell	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1165	P		Seeded From UniProt	complete
involved_in	GO:0046718	viral entry into host cell	GO_REF:0000037 GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1160 UniProtKB-KW:KW-1162	P		Seeded From UniProt	complete
part_of	GO:0019012	virion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0946	C		Seeded From UniProt	complete
involved_in	GO:0039654	fusion of virus membrane with host endosome membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1170	P		Seeded From UniProt	complete
involved_in	GO:0039663	membrane fusion involved in viral entry into host cell	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1168	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0075509	endocytosis involved in viral entry into host cell	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1164	P		Seeded From UniProt	complete
part_of	GO:0044174	host cell endosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1039	C		Seeded From UniProt	complete
part_of	GO:0044175	host cell endosome membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0394	C		Seeded From UniProt	complete
part_of	GO:0055036	virion membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0275	C		Seeded From UniProt	complete
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References

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