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HUMAN:ZN365

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) ZNF365 (synonyms: KIAA0844)
Protein Name(s) Protein ZNF365

Protein su48

External Links
UniProt Q70YC5
EMBL AJ505147
AJ505148
AJ505149
AB020651
AK289515
AK289808
BX647904
AC024597
AC024598
BC017841
BC035049
BC060817
AY547355
CCDS CCDS31209.1
CCDS41531.1
CCDS7264.1
RefSeq NP_055766.2
NP_955522.1
NP_955523.1
UniGene Hs.22653
ProteinModelPortal Q70YC5
BioGrid 116557
DIP DIP-35261N
IntAct Q70YC5
PhosphoSite Q70YC5
BioMuta CACNA1A
DMDM 317373495
PRIDE Q70YC5
DNASU 22891
Ensembl ENST00000395254
ENST00000395255
ENST00000410046
GeneID 22891
KEGG hsa:22891
UCSC uc001jly.4
uc001jlz.4
uc001jmb.4
uc001jmc.2
CTD 22891
GeneCards GC10P062374
HGNC HGNC:18194
HPA HPA052446
MIM 607818
neXtProt NX_Q70YC5
PharmGKB PA134873576
GeneTree ENSGT00530000063713
HOVERGEN HBG094181
InParanoid Q70YC5
KO K16737
OMA SMQPAKS
PhylomeDB Q70YC5
TreeFam TF329439
GenomeRNAi 22891
NextBio 43497
Proteomes UP000005640
Bgee Q70YC5
CleanEx HS_ZNF365
ExpressionAtlas Q70YC5
Genevisible Q70YC5
GO GO:0005737
GO:0005815
InterPro IPR015880
SMART SM00355

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005813

centrosome

PMID:16617106[1]

ECO:0000314

C

Figure 2 shows localization of Su48 at the centrosome. Fluorescence microscopy was used to visualize Su48 inside the cell.

complete
CACAO 11093

involved_in

GO:0010569

regulation of double-strand break repair via homologous recombination

PMID:23966166[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0110026

regulation of DNA strand resection involved in replication fork processing

PMID:23966166[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010977

negative regulation of neuron projection development

PMID:17389905[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0048714

positive regulation of oligodendrocyte differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8BG89

P

Seeded From UniProt

complete

involved_in

GO:0021687

cerebellar molecular layer morphogenesis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8BG89

P

Seeded From UniProt

complete

involved_in

GO:0000723

telomere maintenance

PMID:23776040[4]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0140059

dendrite arborization

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8BG89

P

Seeded From UniProt

complete

involved_in

GO:0060997

dendritic spine morphogenesis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8BG89

P

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005815

microtubule organizing center

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0048714

positive regulation of oligodendrocyte differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q5PQS2
ensembl:ENSRNOP00000054802

P

Seeded From UniProt

complete

involved_in

GO:0140059

dendrite arborization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BG89
ensembl:ENSMUSP00000067197

P

Seeded From UniProt

complete

involved_in

GO:0060997

dendritic spine morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BG89
ensembl:ENSMUSP00000067197

P

Seeded From UniProt

complete

involved_in

GO:0048714

positive regulation of oligodendrocyte differentiation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BG89
ensembl:ENSMUSP00000067197

P

Seeded From UniProt

complete

involved_in

GO:0021687

cerebellar molecular layer morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BG89
ensembl:ENSMUSP00000067197

P

Seeded From UniProt

complete

involved_in

GO:0000723

telomere maintenance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BG89
ensembl:ENSMUSP00000067197

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:16617106[1]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q70YC5-1

F

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

part_of

GO:0005815

microtubule organizing center

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0048

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Wang, Q et al. (2006) Characterization of Su48, a centrosome protein essential for cell division. Proc. Natl. Acad. Sci. U.S.A. 103 6512-7 PubMed GONUTS page
  2. 2.0 2.1 Zhang, Y et al. (2013) ZNF365 promotes stalled replication forks recovery to maintain genome stability. Cell Cycle 12 2817-28 PubMed GONUTS page
  3. Hattori, T et al. (2007) A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth. Mol. Psychiatry 12 398-407 PubMed GONUTS page
  4. Zhang, Y et al. (2013) ZNF365 promotes stability of fragile sites and telomeres. Cancer Discov 3 798-811 PubMed GONUTS page