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HUMAN:YTHD1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | YTHDF1 (synonyms: C20orf21) | |
| Protein Name(s) | YTH domain-containing family protein 1
Dermatomyositis associated with cancer putative autoantigen 1 DACA-1 | |
| External Links | ||
| UniProt | Q9BYJ9 | |
| EMBL | AK000398 AL096828 BC003681 BC016920 BC025264 BC050284 AB055518 AL834366 | |
| CCDS | CCDS13511.1 | |
| RefSeq | NP_060268.2 | |
| UniGene | Hs.744852 | |
| PDB | 4RCI 4RCJ | |
| PDBsum | 4RCI 4RCJ | |
| ProteinModelPortal | Q9BYJ9 | |
| SMR | Q9BYJ9 | |
| BioGrid | 120257 | |
| IntAct | Q9BYJ9 | |
| MINT | MINT-7970439 | |
| STRING | 9606.ENSP00000359364 | |
| PhosphoSite | Q9BYJ9 | |
| DMDM | 28380041 | |
| MaxQB | Q9BYJ9 | |
| PaxDb | Q9BYJ9 | |
| PRIDE | Q9BYJ9 | |
| Ensembl | ENST00000370339 | |
| GeneID | 54915 | |
| KEGG | hsa:54915 | |
| UCSC | uc002yeh.3 | |
| CTD | 54915 | |
| GeneCards | GC20M061826 | |
| HGNC | HGNC:15867 | |
| neXtProt | NX_Q9BYJ9 | |
| PharmGKB | PA25737 | |
| eggNOG | NOG276347 | |
| GeneTree | ENSGT00390000017549 | |
| HOVERGEN | HBG060315 | |
| InParanoid | Q9BYJ9 | |
| OMA | GSKGPVY | |
| OrthoDB | EOG71VSSM | |
| PhylomeDB | Q9BYJ9 | |
| TreeFam | TF323736 | |
| ChiTaRS | YTHDF1 | |
| GenomeRNAi | 54915 | |
| NextBio | 57974 | |
| PMAP-CutDB | Q9BYJ9 | |
| PRO | PR:Q9BYJ9 | |
| Proteomes | UP000005640 | |
| Bgee | Q9BYJ9 | |
| CleanEx | HS_YTHDF1 | |
| ExpressionAtlas | Q9BYJ9 | |
| Genevestigator | Q9BYJ9 | |
| GO | GO:1990247 GO:0044822 | |
| InterPro | IPR007275 | |
| Pfam | PF04146 | |
| PROSITE | PS50882 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0045727 |
positive regulation of translation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045727 |
positive regulation of translation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:1990247 |
N6-methyladenosine-containing RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:1990247 |
N6-methyladenosine-containing RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045948 |
positive regulation of translational initiation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:1990247 |
N6-methyladenosine-containing RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043022 |
ribosome binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:1990247 |
N6-methyladenosine-containing RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:1990247 |
N6-methyladenosine-containing RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Shi, H et al. (2017) YTHDF3 facilitates translation and decay of N-methyladenosine-modified RNA. Cell Res. 27 315-328 PubMed GONUTS page
- ↑ 2.0 2.1 Li, A et al. (2017) Cytoplasmic mA reader YTHDF3 promotes mRNA translation. Cell Res. 27 444-447 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Wang, X et al. (2015) N(6)-methyladenosine Modulates Messenger RNA Translation Efficiency. Cell 161 1388-99 PubMed GONUTS page
- ↑ Xu, C et al. (2015) Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins. J. Biol. Chem. 290 24902-13 PubMed GONUTS page
- ↑ Wang, X et al. (2014) N6-methyladenosine-dependent regulation of messenger RNA stability. Nature 505 117-20 PubMed GONUTS page
- ↑ Castello, A et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149 1393-406 PubMed GONUTS page
- ↑ Baltz, AG et al. (2012) The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell 46 674-90 PubMed GONUTS page
