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HUMAN:WNT6

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) WNT6
Protein Name(s) Protein Wnt-6
External Links
UniProt Q9Y6F9
EMBL AY009401
AB059570
BT007456
BC004329
AF315943
AF079522
CCDS CCDS2425.1
PIR JC7694
RefSeq NP_006513.1
UniGene Hs.29764
ProteinModelPortal Q9Y6F9
SMR Q9Y6F9
STRING 9606.ENSP00000233948
DMDM 14424016
PaxDb Q9Y6F9
PRIDE Q9Y6F9
DNASU 7475
Ensembl ENST00000233948
GeneID 7475
KEGG hsa:7475
UCSC uc002vjc.1
CTD 7475
GeneCards GC02P219724
HGNC HGNC:12785
HPA HPA052031
MIM 604663
neXtProt NX_Q9Y6F9
PharmGKB PA37386
eggNOG NOG246444
GeneTree ENSGT00760000118943
HOGENOM HOG000039528
HOVERGEN HBG001595
InParanoid Q9Y6F9
KO K00445
OMA CGCEATR
OrthoDB EOG7C8GJ8
PhylomeDB Q9Y6F9
TreeFam TF105310
Reactome REACT_163710
REACT_18372
GenomeRNAi 7475
NextBio 29280
PRO PR:Q9Y6F9
Proteomes UP000005640
Bgee Q9Y6F9
CleanEx HS_WNT6
ExpressionAtlas Q9Y6F9
Genevestigator Q9Y6F9
GO GO:0009986
GO:0005788
GO:0005576
GO:0005615
GO:0005796
GO:0005886
GO:0005578
GO:0005109
GO:0009798
GO:0001658
GO:0045165
GO:0071300
GO:0061303
GO:0060684
GO:0072079
GO:0030182
GO:0042475
GO:0010628
GO:0070172
GO:0045893
GO:0016055
InterPro IPR005817
IPR009143
IPR018161
PANTHER PTHR12027
Pfam PF00110
PRINTS PR01845
PR01349
SMART SM00097
PROSITE PS00246

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0070172

positive regulation of tooth mineralization

PMID:20113781[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0061303

cornea development in camera-type eye

PMID:16258938[2]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q3C2H6

P

Seeded From UniProt

complete

involved_in

GO:0042475

odontogenesis of dentin-containing tooth

PMID:20113781[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

PMID:20113781[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071300

cellular response to retinoic acid

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P56706

P

Seeded From UniProt

complete

involved_in

GO:0030182

neuron differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P56706

P

Seeded From UniProt

complete

involved_in

GO:0045165

cell fate commitment

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98957
PANTHER:PTN000246517
UniProtKB:P49339
ZFIN:ZDB-GENE-980526-332

P

Seeded From UniProt

complete

involved_in

GO:0030182

neuron differentiation

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000246517
RGD:69250
UniProtKB:P56706
UniProtKB:Q98SN7

P

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0010194
MGI:MGI:108061
MGI:MGI:1197020
MGI:MGI:98953
MGI:MGI:98954
MGI:MGI:98956
MGI:MGI:98958
MGI:MGI:98960
MGI:MGI:98961
MGI:MGI:98962
PANTHER:PTN000246517
UniProtKB:P41221
UniProtKB:Q98SN7
WB:WBGene00000858
WB:WBGene00003029
ZFIN:ZDB-GENE-980526-332

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004009
MGI:MGI:98956
MGI:MGI:98957
PANTHER:PTN000246517
RGD:1311441
RGD:69250
UniProtKB:P41221
UniProtKB:P56704
UniProtKB:P56705
UniProtKB:Q2LMP1
UniProtKB:Q9UBV4
UniProtKB:Q9YGX6

C

Seeded From UniProt

complete

enables

GO:0005109

frizzled binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004009
FB:FBgn0004360
FB:FBgn0010453
FB:FBgn0038134
MGI:MGI:98956
MGI:MGI:98957
MGI:MGI:98958
MGI:MGI:98961
MGI:MGI:98962
PANTHER:PTN000246517
RGD:69079
UniProtKB:P09544
UniProtKB:P41221
UniProtKB:P56703
UniProtKB:Q98SN7

F

Seeded From UniProt

complete

involved_in

GO:0072080

nephron tubule development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22727
ensembl:ENSMUSP00000006716

P

Seeded From UniProt

complete

involved_in

GO:0072079

nephron tubule formation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22727
ensembl:ENSMUSP00000006716

P

Seeded From UniProt

complete

involved_in

GO:0060684

epithelial-mesenchymal cell signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22727
ensembl:ENSMUSP00000006716

P

Seeded From UniProt

complete

involved_in

GO:0045893

positive regulation of transcription, DNA-templated

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22727
ensembl:ENSMUSP00000006716

P

Seeded From UniProt

complete

part_of

GO:0031012

extracellular matrix

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22727
ensembl:ENSMUSP00000006716

C

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22727
ensembl:ENSMUSP00000006716

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22727
ensembl:ENSMUSP00000006716

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22727
ensembl:ENSMUSP00000006716

C

Seeded From UniProt

complete

involved_in

GO:0009798

axis specification

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22727
ensembl:ENSMUSP00000006716

P

Seeded From UniProt

complete

involved_in

GO:0001658

branching involved in ureteric bud morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P22727
ensembl:ENSMUSP00000006716

P

Seeded From UniProt

complete

enables

GO:0005102

signaling receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005817
InterPro:IPR009143

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005817
InterPro:IPR009143

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005817
InterPro:IPR009143

P

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005817
InterPro:IPR009143

P

Seeded From UniProt

complete

part_of

GO:0070062

extracellular exosome

Reactome:R-HSA-3781941

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030666

endocytic vesicle membrane

Reactome:R-HSA-3781943
Reactome:R-HSA-3781941

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

Reactome:R-HSA-195721

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-HSA-3781943
Reactome:R-HSA-3247844
Reactome:R-HSA-3247843

ECO:0000304

author statement supported by traceable reference used in manual assertion



C

Seeded From UniProt

complete

part_of

GO:0005796

Golgi lumen

Reactome:R-HSA-3247844
Reactome:R-HSA-3247840
Reactome:R-HSA-3247837

ECO:0000304

author statement supported by traceable reference used in manual assertion



C

Seeded From UniProt

complete

part_of

GO:0005788

endoplasmic reticulum lumen

Reactome:R-HSA-3247837

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

Reactome:R-HSA-3247843

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0879

P

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 Wang, C et al. (2010) Effect of Wnt6 on human dental papilla cells in vitro. J Endod 36 238-43 PubMed GONUTS page
  2. ↑ Fokina, VM & Frolova, EI (2006) Expression patterns of Wnt genes during development of an anterior part of the chicken eye. Dev. Dyn. 235 496-505 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 3.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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