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HUMAN:UT2

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) SLC14A2 (synonyms: HUT2, UT2)
Protein Name(s) Urea transporter 2

Solute carrier family 14 member 2 Urea transporter, kidney

External Links
UniProt Q15849
EMBL X96969
AF349446
AK292422
AC023421
BC110446
CCDS CCDS11924.1
PIR S71339
RefSeq NP_001229621.1
NP_009094.3
UniGene Hs.710927
ProteinModelPortal Q15849
SMR Q15849
IntAct Q15849
STRING 9606.ENSP00000255226
TCDB 1.A.28.1.6
PhosphoSite Q15849
DMDM 292495053
PaxDb Q15849
PRIDE Q15849
Ensembl ENST00000255226
ENST00000586448
ENST00000589658
GeneID 8170
KEGG hsa:8170
UCSC uc002lbe.3
CTD 8170
GeneCards GC18P042792
H-InvDB HIX0014422
HGNC HGNC:10919
HPA HPA050069
MIM 601611
neXtProt NX_Q15849
PharmGKB PA35811
eggNOG COG4413
GeneTree ENSGT00390000018729
HOGENOM HOG000168437
HOVERGEN HBG073255
InParanoid Q15849
KO K08716
OMA VCALFCA
OrthoDB EOG7GBFX8
PhylomeDB Q15849
Reactome REACT_19305
ChiTaRS SLC14A2
GeneWiki SLC14A2
GenomeRNAi 8170
NextBio 30845
PRO PR:Q15849
Proteomes UP000005640
Bgee Q15849
CleanEx HS_SLC14A2
ExpressionAtlas Q15849
Genevestigator Q15849
GO GO:0016324
GO:0016021
GO:0016020
GO:0005886
GO:0050839
GO:0015204
GO:0055085
GO:0015840
Gene3D 1.10.3430.10
InterPro IPR029020
IPR004937
PANTHER PTHR10464
Pfam PF03253

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0071918

urea transmembrane transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1351653
MGI:MGI:1351654
PANTHER:PTN002573341
RGD:3688
RGD:3689
UniProtKB:Q13336
UniProtKB:Q5QF96

P

Seeded From UniProt

complete

involved_in

GO:0015840

urea transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1351653
MGI:MGI:1351654
PANTHER:PTN002573341
RGD:3688
RGD:3689
UniProtKB:Q13336
UniProtKB:Q5QF96
ZFIN:ZDB-GENE-030131-4833

P

Seeded From UniProt

complete

enables

GO:0015265

urea channel activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001627166
UniProtKB:Q13336
UniProtKB:Q5QF96

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001627166
UniProtKB:Q13336
UniProtKB:Q5QF96

C

Seeded From UniProt

complete

enables

GO:0050839

cell adhesion molecule binding

PMID:23620790[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015204

urea transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004937

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004937

C

Seeded From UniProt

complete

involved_in

GO:0071918

urea transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004937

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

PMID:8647271[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:8647271[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0015840

urea transport

PMID:8647271[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0015204

urea transmembrane transporter activity

PMID:8647271[3]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

Reactome:R-HSA-425407

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

Reactome:R-HSA-444126

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0015

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Chiang, YJ et al. (2013) CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration. PLoS ONE 8 e61761 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Olivès, B et al. (1996) Molecular characterization of a new urea transporter in the human kidney. FEBS Lett. 386 156-60 PubMed GONUTS page