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HUMAN:TXLNA
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | TXLNA (synonyms: TXLN) | |
| Protein Name(s) | Alpha-taxilin | |
| External Links | ||
| UniProt | P40222 | |
| EMBL | AF516206 AL832636 AL832637 AL832338 AL049795 CH471059 CH471059 BC029686 BC046565 BC080578 BC103823 BC103824 L15344 | |
| CCDS | CCDS353.1 | |
| PIR | A48203 | |
| RefSeq | NP_787048.1 | |
| UniGene | Hs.17987 | |
| ProteinModelPortal | P40222 | |
| BioGrid | 128297 | |
| DIP | DIP-27612N | |
| IntAct | P40222 | |
| MINT | MINT-1150979 | |
| STRING | 9606.ENSP00000362711 | |
| iPTMnet | P40222 | |
| PhosphoSite | P40222 | |
| SwissPalm | P40222 | |
| BioMuta | TXLNA | |
| DMDM | 55584162 | |
| EPD | P40222 | |
| MaxQB | P40222 | |
| PaxDb | P40222 | |
| PeptideAtlas | P40222 | |
| PRIDE | P40222 | |
| DNASU | 200081 | |
| Ensembl | ENST00000373609 ENST00000373610 | |
| GeneID | 200081 | |
| KEGG | hsa:200081 | |
| UCSC | uc001bui.4 | |
| CTD | 200081 | |
| GeneCards | TXLNA | |
| HGNC | HGNC:30685 | |
| HPA | HPA045383 | |
| MIM | 608676 | |
| neXtProt | NX_P40222 | |
| PharmGKB | PA142670668 | |
| eggNOG | KOG1850 ENOG410XQH1 | |
| GeneTree | ENSGT00390000001482 | |
| HOVERGEN | HBG104385 | |
| InParanoid | P40222 | |
| OMA | RKPEGAQ | |
| OrthoDB | EOG70KGP6 | |
| PhylomeDB | P40222 | |
| TreeFam | TF318595 | |
| Reactome | [www.reactome.org/content/detail/R-HSA-449147 R-HSA-449147] | |
| ChiTaRS | TXLNA | |
| GeneWiki | TXLNA | |
| GenomeRNAi | 200081 | |
| PRO | PR:P40222 | |
| Proteomes | UP000005640 | |
| Bgee | P40222 | |
| Genevisible | P40222 | |
| GO | GO:0005737 GO:0005576 GO:0016020 GO:0005125 GO:0030372 GO:0042113 GO:0008283 GO:0006887 GO:0098779 | |
| InterPro | IPR026183 | |
| PANTHER | PTHR16127 | |
| Pfam | PF09728 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0016020 |
membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030372 |
high molecular weight B cell growth factor receptor binding |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008283 |
cell population proliferation |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000303 |
author statement without traceable support used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005125 |
cytokine activity |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005125 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042113 |
B cell activation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q6PAM1 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019905 |
syntaxin binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019221 |
cytokine-mediated signaling pathway |
Reactome:R-HSA-449836 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-9014074 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0006887 |
exocytosis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
| GO:1905476 |
negative regulation of protein localization to membrane |
ECO:0000315 |
P |
Figure 5c: cells with elevated expression of alpha-taxilin show decreased binding of insulin to receptors on cell membrane, indicating decreased insulin receptors in the membrane. |
complete | |||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Ambrus, JL Jr et al. (1993) Identification of a cDNA for a human high-molecular-weight B-cell growth factor. Proc. Natl. Acad. Sci. U.S.A. 90 6330-4 PubMed GONUTS page
- ↑ Barthel, SR et al. (2016) Hepatitis B virus inhibits insulin receptor signaling and impairs liver regeneration via intracellular retention of the insulin receptor. Cell. Mol. Life Sci. 73 4121-40 PubMed GONUTS page
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