GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

HUMAN:TTPA

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) TTPA (synonyms: TPP1)
Protein Name(s) Alpha-tocopherol transfer protein

Alpha-TTP

External Links
UniProt P49638
EMBL D49488
U21938
BC058000
AH006950
CCDS CCDS6178.1
PIR S54352
RefSeq NP_000361.1
UniGene Hs.69049
PDB 1OIP
1OIZ
1R5L
PDBsum 1OIP
1OIZ
1R5L
ProteinModelPortal P49638
SMR P49638
BioGrid 113125
STRING 9606.ENSP00000260116
DrugBank DB00163
PhosphoSite P49638
DMDM 1351322
MaxQB P49638
PaxDb P49638
PRIDE P49638
DNASU 7274
Ensembl ENST00000260116
GeneID 7274
KEGG hsa:7274
UCSC uc003xux.2
CTD 7274
GeneCards GC08M063961
GeneReviews TTPA
HGNC HGNC:12404
MIM 277460
600415
neXtProt NX_P49638
Orphanet 96
PharmGKB PA37068
eggNOG NOG250577
GeneTree ENSGT00550000074253
HOGENOM HOG000231534
HOVERGEN HBG018009
InParanoid P49638
OMA WRFAHAF
OrthoDB EOG7H4DTZ
PhylomeDB P49638
EvolutionaryTrace P49638
GeneWiki Alpha-tocopherol_transfer_protein
GenomeRNAi 7274
NextBio 28443
PRO PR:P49638
Proteomes UP000005640
Bgee P49638
CleanEx HS_TPP1
HS_TTPA
Genevestigator P49638
GO GO:0005829
GO:0005770
GO:0043325
GO:0005546
GO:0005215
GO:0008431
GO:0001892
GO:0046909
GO:0051452
GO:0006629
GO:0060548
GO:0090212
GO:0007584
GO:0009268
GO:0009636
GO:0006810
GO:0042360
GO:0051180
Gene3D 3.40.525.10
InterPro IPR001071
IPR001251
IPR011074
Pfam PF00650
PF03765
PRINTS PR00180
SMART SM01100
SM00516
SUPFAM SSF46938
SSF52087
PROSITE PS50191

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0051180

vitamin transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8BWP5

P

Seeded From UniProt

complete

involved_in

GO:0120009

intermembrane lipid transfer

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8BWP5

P

Seeded From UniProt

complete

enables

GO:0043325

phosphatidylinositol-3,4-bisphosphate binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8BWP5

F

Seeded From UniProt

complete

enables

GO:0008431

vitamin E binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8BWP5

F

Seeded From UniProt

complete

enables

GO:0005546

phosphatidylinositol-4,5-bisphosphate binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8BWP5

F

Seeded From UniProt

complete

enables

GO:0120013

intermembrane lipid transfer activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1354168
PANTHER:PTN002360048

F

Seeded From UniProt

complete

involved_in

GO:0051180

vitamin transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1354168
PANTHER:PTN002360048

P

Seeded From UniProt

complete

involved_in

GO:0042360

vitamin E metabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1354168
PANTHER:PTN002360048
RGD:3915

P

Seeded From UniProt

complete

enables

GO:0008431

vitamin E binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1354168
PANTHER:PTN002360048
RGD:3915

F

Seeded From UniProt

complete

part_of

GO:0005770

late endosome

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002360048
RGD:3915

C

Seeded From UniProt

complete

involved_in

GO:0060548

negative regulation of cell death

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P41034
ensembl:ENSRNOP00000009611

P

Seeded From UniProt

complete

involved_in

GO:0051452

intracellular pH reduction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P41034
ensembl:ENSRNOP00000009611

P

Seeded From UniProt

complete

involved_in

GO:0042360

vitamin E metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P41034
ensembl:ENSRNOP00000009611

P

Seeded From UniProt

complete

involved_in

GO:0032502

developmental process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P41034
ensembl:ENSRNOP00000009611

P

Seeded From UniProt

complete

enables

GO:0019842

vitamin binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P41034
ensembl:ENSRNOP00000009611

F

Seeded From UniProt

complete

involved_in

GO:0009268

response to pH

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P41034
ensembl:ENSRNOP00000009611

P

Seeded From UniProt

complete

enables

GO:0008431

vitamin E binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P41034
ensembl:ENSRNOP00000009611

F

Seeded From UniProt

complete

involved_in

GO:0007584

response to nutrient

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P41034
ensembl:ENSRNOP00000009611

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P41034
ensembl:ENSRNOP00000009611

C

Seeded From UniProt

complete

part_of

GO:0005770

late endosome

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P41034
ensembl:ENSRNOP00000009611

C

Seeded From UniProt

complete

enables

GO:0120013

intermembrane lipid transfer activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BWP5
ensembl:ENSMUSP00000095845

F

Seeded From UniProt

complete

involved_in

GO:0120009

intermembrane lipid transfer

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BWP5
ensembl:ENSMUSP00000095845

P

Seeded From UniProt

complete

involved_in

GO:0090212

negative regulation of establishment of blood-brain barrier

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BWP5
ensembl:ENSMUSP00000095845

P

Seeded From UniProt

complete

involved_in

GO:0051180

vitamin transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BWP5
ensembl:ENSMUSP00000095845

P

Seeded From UniProt

complete

enables

GO:0043325

phosphatidylinositol-3,4-bisphosphate binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BWP5
ensembl:ENSMUSP00000095845

F

Seeded From UniProt

complete

involved_in

GO:0042360

vitamin E metabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BWP5
ensembl:ENSMUSP00000095845

P

Seeded From UniProt

complete

involved_in

GO:0009636

response to toxic substance

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BWP5
ensembl:ENSMUSP00000095845

P

Seeded From UniProt

complete

enables

GO:0008431

vitamin E binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BWP5
ensembl:ENSMUSP00000095845

F

Seeded From UniProt

complete

enables

GO:0005546

phosphatidylinositol-4,5-bisphosphate binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BWP5
ensembl:ENSMUSP00000095845

F

Seeded From UniProt

complete

involved_in

GO:0001892

embryonic placenta development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BWP5
ensembl:ENSMUSP00000095845

P

Seeded From UniProt

complete

involved_in

GO:0001890

placenta development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BWP5
ensembl:ENSMUSP00000095845

P

Seeded From UniProt

complete

enables

GO:0008431

vitamin E binding

PMID:7887897[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

PMID:7887897[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0042360

vitamin E metabolic process

Reactome:R-HSA-8877627

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-8874718
Reactome:R-HSA-8874705

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0008289

lipid binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0446

F

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. ↑ 2.0 2.1 Arita, M et al. (1995) Human alpha-tocopherol transfer protein: cDNA cloning, expression and chromosomal localization. Biochem. J. 306 ( Pt 2) 437-43 PubMed GONUTS page
Retrieved from "https://gowiki.tamu.edu/wiki/index.php?title=HUMAN:TTPA&oldid=5957525"