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HUMAN:TRNT1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | TRNT1 | |
| Protein Name(s) | CCA tRNA nucleotidyltransferase 1, mitochondrial
Mitochondrial tRNA nucleotidyl transferase, CCA-adding mt CCA-adding enzyme mt tRNA CCA-diphosphorylase mt tRNA CCA-pyrophosphorylase mt tRNA adenylyltransferase | |
| External Links | ||
| UniProt | Q96Q11 | |
| EMBL | AB063105 AF151805 AK290411 AL834397 AC024060 CH471055 BC005184 BC012537 | |
| CCDS | CCDS2561.2 | |
| RefSeq | NP_886552.2 XP_005265253.1 | |
| UniGene | Hs.732725 | |
| PDB | 1OU5 | |
| PDBsum | 1OU5 | |
| ProteinModelPortal | Q96Q11 | |
| SMR | Q96Q11 | |
| BioGrid | 119284 | |
| IntAct | Q96Q11 | |
| MINT | MINT-4725447 | |
| STRING | 9606.ENSP00000251607 | |
| PhosphoSite | Q96Q11 | |
| DMDM | 296452848 | |
| MaxQB | Q96Q11 | |
| PaxDb | Q96Q11 | |
| PRIDE | Q96Q11 | |
| DNASU | 51095 | |
| Ensembl | ENST00000251607 ENST00000280591 ENST00000339437 ENST00000402675 ENST00000420393 ENST00000434583 | |
| GeneID | 51095 | |
| KEGG | hsa:51095 | |
| UCSC | uc003bpp.4 uc010hbv.3 | |
| CTD | 51095 | |
| GeneCards | GC03P003168 | |
| HGNC | HGNC:17341 | |
| HPA | HPA036938 | |
| MIM | 612907 | |
| neXtProt | NX_Q96Q11 | |
| PharmGKB | PA38446 | |
| eggNOG | COG0617 | |
| GeneTree | ENSGT00390000009678 | |
| HOGENOM | HOG000253345 | |
| HOVERGEN | HBG061403 | |
| InParanoid | Q96Q11 | |
| KO | K00974 | |
| OMA | FPVSGHD | |
| OrthoDB | EOG7CCBR5 | |
| PhylomeDB | Q96Q11 | |
| TreeFam | TF313253 | |
| BRENDA | 2.7.7.21 | |
| ChiTaRS | TRNT1 | |
| EvolutionaryTrace | Q96Q11 | |
| GeneWiki | TRNT1 | |
| GenomeRNAi | 51095 | |
| NextBio | 53789 | |
| PRO | PR:Q96Q11 | |
| Proteomes | UP000005640 | |
| Bgee | Q96Q11 | |
| CleanEx | HS_TRNT1 | |
| ExpressionAtlas | Q96Q11 | |
| Genevestigator | Q96Q11 | |
| GO | GO:0005622 GO:0005739 GO:0005524 GO:0052929 GO:0052928 GO:0052927 GO:0004810 GO:0000049 GO:0006626 GO:0042780 GO:0001680 | |
| InterPro | IPR002646 | |
| Pfam | PF01743 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0001680 |
tRNA 3'-terminal CCA addition |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005622 |
intracellular |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1990180 |
mitochondrial tRNA 3'-end processing |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0052929 |
ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000049 |
tRNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006396 |
RNA processing |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016779 |
nucleotidyltransferase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0052928 |
CTP:3'-cytidine-tRNA cytidylyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0052927 |
CTP:tRNA cytidylyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0052929 |
ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1990180 |
mitochondrial tRNA 3'-end processing |
Reactome:R-HSA-6786881 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042780 |
tRNA 3'-end processing |
Reactome:R-HSA-5696807 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0034062 |
5'-3' RNA polymerase activity |
Reactome:R-HSA-6786881 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
F |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005759 |
mitochondrial matrix |
Reactome:R-HSA-6786881 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005654 |
nucleoplasm |
Reactome:R-HSA-5696807 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008033 |
tRNA processing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016779 |
nucleotidyltransferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Chakraborty, PK et al. (2014) Mutations in TRNT1 cause congenital sideroblastic anemia with immunodeficiency, fevers, and developmental delay (SIFD). Blood 124 2867-71 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Nagaike, T et al. (2001) Identification and characterization of mammalian mitochondrial tRNA nucleotidyltransferases. J. Biol. Chem. 276 40041-9 PubMed GONUTS page
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