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HUMAN:TPPP3

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) TPPP3
Protein Name(s) Tubulin polymerization-promoting protein family member 3

TPPP/p20

External Links
UniProt Q9BW30
EMBL AF132972
AF078846
BC000691
CCDS CCDS10835.1
RefSeq NP_057048.2
NP_057224.2
UniGene Hs.534458
PDB 2JRF
PDBsum 2JRF
ProteinModelPortal Q9BW30
SMR Q9BW30
BioGrid 119673
PhosphoSite Q9BW30
DMDM 28380040
MaxQB Q9BW30
PaxDb Q9BW30
PeptideAtlas Q9BW30
PRIDE Q9BW30
DNASU 51673
Ensembl ENST00000290942
ENST00000393957
ENST00000562206
ENST00000564104
GeneID 51673
KEGG hsa:51673
UCSC uc002esz.3
CTD 51673
GeneCards GC16M067423
HGNC HGNC:24162
HPA HPA047629
neXtProt NX_Q9BW30
PharmGKB PA162406823
eggNOG NOG271804
GeneTree ENSGT00390000014993
HOGENOM HOG000260314
HOVERGEN HBG036683
InParanoid Q9BW30
OMA ELNGKNW
OrthoDB EOG7NGQDH
PhylomeDB Q9BW30
TreeFam TF314440
ChiTaRS TPPP3
EvolutionaryTrace Q9BW30
GenomeRNAi 51673
NextBio 55672
PRO PR:Q9BW30
Proteomes UP000005640
Bgee Q9BW30
CleanEx HS_TPPP3
ExpressionAtlas Q9BW30
Genevestigator Q9BW30
GO GO:0005737
GO:0070062
GO:0005874
GO:0015631
GO:0001578
InterPro IPR008907
PANTHER PTHR12932
Pfam PF05517

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0031110

regulation of microtubule polymerization or depolymerization

PMID:19235716[1]

ECO:0000314

P

Fig 1 and Fig 2

complete

colocalizes_with

GO:0097427

microtubule bundle

PMID:17105200[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

colocalizes_with

GO:0048471

perinuclear region of cytoplasm

PMID:17105200[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0015631

tubulin binding

PMID:17105200[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0001578

microtubule bundle formation

PMID:17105200[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0046785

microtubule polymerization

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0266417
MGI:MGI:1920198
PANTHER:PTN000309419
UniProtKB:O94811
UniProtKB:Q27957

P

Seeded From UniProt

complete

involved_in

GO:0032273

positive regulation of protein polymerization

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000309419
UniProtKB:O94811

P

Seeded From UniProt

complete

enables

GO:0015631

tubulin binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000309419
UniProtKB:O94811
UniProtKB:P59282
UniProtKB:Q27957
UniProtKB:Q9BW30

F

Seeded From UniProt

complete

colocalizes_with

GO:0005874

microtubule

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1920198
PANTHER:PTN000309419
UniProtKB:O94811

C

Seeded From UniProt

complete

involved_in

GO:0001578

microtubule bundle formation

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0266417
PANTHER:PTN000309419
UniProtKB:O94811
UniProtKB:P59282
UniProtKB:Q27957
UniProtKB:Q9BW30

P

Seeded From UniProt

complete

involved_in

GO:0001578

microtubule bundle formation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030795

P

Seeded From UniProt

complete

enables

GO:0015631

tubulin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030795

F

Seeded From UniProt

complete

involved_in

GO:0046785

microtubule polymerization

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR030795

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

part_of

GO:0005874

microtubule

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0493

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Staverosky, JA et al. (2009) Tubulin polymerization-promoting protein family member 3, Tppp3, is a specific marker of the differentiating tendon sheath and synovial joints. Dev. Dyn. 238 685-92 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Vincze, O et al. (2006) Tubulin polymerization promoting proteins (TPPPs): members of a new family with distinct structures and functions. Biochemistry 45 13818-26 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page