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HUMAN:TNIP3

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) TNIP3 (ECO:0000312 with HGNC:HGNC:19315) (synonyms: ABIN3, LIND)
Protein Name(s) TNFAIP3-interacting protein 3

A20-binding inhibitor of NF-kappa-B activation 3 ABIN-3 Listeria-induced gene protein

External Links
UniProt Q96KP6
EMBL AF277289
AJ320534
AK024815
AK290409
AK301058
AK303192
AC105254
AC108027
CH471056
BC128408
CCDS CCDS3718.1
CCDS58925.1
CCDS58926.1
RefSeq NP_001122315.2
NP_001231693.1
NP_079149.3
UniGene Hs.208206
ProteinModelPortal Q96KP6
BioGrid 123006
IntAct Q96KP6
STRING 9606.ENSP00000057513
PhosphoSite Q96KP6
DMDM 269849474
PaxDb Q96KP6
PRIDE Q96KP6
Ensembl ENST00000057513
ENST00000507879
ENST00000509841
GeneID 79931
KEGG hsa:79931
UCSC uc010ing.3
uc011cgj.2
uc021xrj.1
CTD 79931
GeneCards GC04M122052
H-InvDB HIX0004478
HGNC HGNC:19315
HPA HPA043063
MIM 608019
neXtProt NX_Q96KP6
PharmGKB PA134934429
eggNOG NOG43556
GeneTree ENSGT00510000046908
HOGENOM HOG000013050
HOVERGEN HBG069354
InParanoid Q96KP6
OMA LEQKIRC
OrthoDB EOG7SJD44
PhylomeDB Q96KP6
TreeFam TF351138
GenomeRNAi 79931
NextBio 69856
PRO PR:Q96KP6
Proteomes UP000005640
Bgee Q96KP6
CleanEx HS_TNIP3
ExpressionAtlas Q96KP6
Genevestigator Q96KP6
GO GO:0031593
GO:0071222
GO:0006954
GO:0002756
GO:0043124
GO:0034142

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0071222

cellular response to lipopolysaccharide

PMID:17088249[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043124

negative regulation of I-kappaB kinase/NF-kappaB signaling

PMID:17088249[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0034142

toll-like receptor 4 signaling pathway

PMID:17088249[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0031593

polyubiquitin modification-dependent protein binding

PMID:18212736[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0002756

MyD88-independent toll-like receptor signaling pathway

PMID:17088249[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0043124

negative regulation of I-kappaB kinase/NF-kappaB signaling

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033574

P

Seeded From UniProt

complete

involved_in

GO:0071222

cellular response to lipopolysaccharide

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR033574

P

Seeded From UniProt

complete

involved_in

GO:0016579

protein deubiquitination

Reactome:R-HSA-5688426

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-5690845

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006954

inflammatory response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0395

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Wullaert, A et al. (2007) LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activation. J. Biol. Chem. 282 81-90 PubMed GONUTS page
  2. Wagner, S et al. (2008) Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins. Oncogene 27 3739-45 PubMed GONUTS page