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HUMAN:TNIP3
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | TNIP3 (ECO:0000312 with HGNC:HGNC:19315) (synonyms: ABIN3, LIND) | |
Protein Name(s) | TNFAIP3-interacting protein 3
A20-binding inhibitor of NF-kappa-B activation 3 ABIN-3 Listeria-induced gene protein | |
External Links | ||
UniProt | Q96KP6 | |
EMBL | AF277289 AJ320534 AK024815 AK290409 AK301058 AK303192 AC105254 AC108027 CH471056 BC128408 | |
CCDS | CCDS3718.1 CCDS58925.1 CCDS58926.1 | |
RefSeq | NP_001122315.2 NP_001231693.1 NP_079149.3 | |
UniGene | Hs.208206 | |
ProteinModelPortal | Q96KP6 | |
BioGrid | 123006 | |
IntAct | Q96KP6 | |
STRING | 9606.ENSP00000057513 | |
PhosphoSite | Q96KP6 | |
DMDM | 269849474 | |
PaxDb | Q96KP6 | |
PRIDE | Q96KP6 | |
Ensembl | ENST00000057513 ENST00000507879 ENST00000509841 | |
GeneID | 79931 | |
KEGG | hsa:79931 | |
UCSC | uc010ing.3 uc011cgj.2 uc021xrj.1 | |
CTD | 79931 | |
GeneCards | GC04M122052 | |
H-InvDB | HIX0004478 | |
HGNC | HGNC:19315 | |
HPA | HPA043063 | |
MIM | 608019 | |
neXtProt | NX_Q96KP6 | |
PharmGKB | PA134934429 | |
eggNOG | NOG43556 | |
GeneTree | ENSGT00510000046908 | |
HOGENOM | HOG000013050 | |
HOVERGEN | HBG069354 | |
InParanoid | Q96KP6 | |
OMA | LEQKIRC | |
OrthoDB | EOG7SJD44 | |
PhylomeDB | Q96KP6 | |
TreeFam | TF351138 | |
GenomeRNAi | 79931 | |
NextBio | 69856 | |
PRO | PR:Q96KP6 | |
Proteomes | UP000005640 | |
Bgee | Q96KP6 | |
CleanEx | HS_TNIP3 | |
ExpressionAtlas | Q96KP6 | |
Genevestigator | Q96KP6 | |
GO | GO:0031593 GO:0071222 GO:0006954 GO:0002756 GO:0043124 GO:0034142 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0071222 |
cellular response to lipopolysaccharide |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043124 |
negative regulation of I-kappaB kinase/NF-kappaB signaling |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0034142 |
toll-like receptor 4 signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0031593 |
polyubiquitin modification-dependent protein binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0002756 |
MyD88-independent toll-like receptor signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043124 |
negative regulation of I-kappaB kinase/NF-kappaB signaling |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0071222 |
cellular response to lipopolysaccharide |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016579 |
protein deubiquitination |
Reactome:R-HSA-5688426 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-5690845 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006954 |
inflammatory response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Wullaert, A et al. (2007) LIND/ABIN-3 is a novel lipopolysaccharide-inducible inhibitor of NF-kappaB activation. J. Biol. Chem. 282 81-90 PubMed GONUTS page
- ↑ Wagner, S et al. (2008) Ubiquitin binding mediates the NF-kappaB inhibitory potential of ABIN proteins. Oncogene 27 3739-45 PubMed GONUTS page