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HUMAN:SPB5

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) SERPINB5 (synonyms: PI5)
Protein Name(s) Serpin B5

Maspin Peptidase inhibitor 5 PI-5

External Links
UniProt P36952
EMBL U04313
AK312765
AC036176
BC020713
BX640597
CCDS CCDS32839.1
PIR A36898
RefSeq NP_002630.2
UniGene Hs.55279
PDB 1WZ9
1XQG
1XQJ
1XU8
PDBsum 1WZ9
1XQG
1XQJ
1XU8
ProteinModelPortal P36952
SMR P36952
BioGrid 111286
IntAct P36952
MINT MINT-7712082
STRING 9606.ENSP00000372221
MEROPS I04.980
PhosphoSite P36952
DMDM 229462757
MaxQB P36952
PaxDb P36952
PRIDE P36952
DNASU 5268
Ensembl ENST00000382771
ENST00000489441
GeneID 5268
KEGG hsa:5268
UCSC uc002liy.2
uc002liz.4
CTD 5268
GeneCards GC18P061117
H-InvDB HIX0014501
HGNC HGNC:8949
HPA CAB009570
HPA019025
HPA019132
HPA020136
MIM 154790
neXtProt NX_P36952
PharmGKB PA35515
eggNOG COG4826
GeneTree ENSGT00760000118789
HOGENOM HOG000238519
HOVERGEN HBG005957
InParanoid P36952
KO K10139
OMA DTADQMK
OrthoDB EOG7327PB
PhylomeDB P36952
TreeFam TF352619
ChiTaRS SERPINB5
EvolutionaryTrace P36952
GeneWiki Maspin
GenomeRNAi 5268
NextBio 20352
PRO PR:P36952
Proteomes UP000005640
Bgee P36952
CleanEx HS_SERPINB5
ExpressionAtlas P36952
Genevestigator P36952
GO GO:0005737
GO:0005615
GO:0070062
GO:0004867
GO:0006928
GO:0030198
GO:0002009
GO:0010951
GO:0060512
GO:0050678
GO:0030162
InterPro IPR000240
IPR023795
IPR023796
IPR000215
PANTHER PTHR11461
Pfam PF00079
PRINTS PR00676
SMART SM00093
SUPFAM SSF56574
PROSITE PS00284

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005737

cytoplasm

PMID:16049006[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0010951

negative regulation of endopeptidase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0028988
FB:FBgn0265137
PANTHER:PTN000156123
RGD:3249
UniProtKB:P05121
UniProtKB:P29508
UniProtKB:P35237
UniProtKB:P50452
UniProtKB:P50453
UniProtKB:Q9UIV8

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0002930
FB:FBgn0015586
FB:FBgn0028986
FB:FBgn0031973
FB:FBgn0262057
FB:FBgn0265137
MGI:MGI:108080
MGI:MGI:1915304
MGI:MGI:87963
MGI:MGI:88278
MGI:MGI:894696
PANTHER:PTN000156123
RGD:1306692
RGD:1307404
RGD:2069
RGD:3249
RGD:3326
RGD:3747
RGD:3748
RGD:619833
RGD:631369
RGD:735225
UniProtKB:P01008
UniProtKB:P01009
UniProtKB:P01011
UniProtKB:P01019
UniProtKB:P05121
UniProtKB:P05154
UniProtKB:P08697
UniProtKB:P50453
UniProtKB:Q90935
UniProtKB:Q99574
UniProtKB:Q9TTE1

C

Seeded From UniProt

complete

enables

GO:0004867

serine-type endopeptidase inhibitor activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0002930
FB:FBgn0028983
FB:FBgn0028988
FB:FBgn0028990
FB:FBgn0265137
MGI:MGI:101780
MGI:MGI:106603
MGI:MGI:1277952
MGI:MGI:2445361
MGI:MGI:2683293
MGI:MGI:891970
MGI:MGI:894696
MGI:MGI:97608
PANTHER:PTN000156123
RGD:1306692
RGD:1307404
RGD:3249
RGD:3326
RGD:3748
RGD:619817
RGD:619896
RGD:619897
UniProtKB:P01009
UniProtKB:P01012
UniProtKB:P05121
UniProtKB:P05154
UniProtKB:P05155
UniProtKB:P07093
UniProtKB:P08697
UniProtKB:P35237
UniProtKB:P48594
UniProtKB:P50452
UniProtKB:P50453
UniProtKB:Q3ZEJ6
UniProtKB:Q86WD7
UniProtKB:Q90935
UniProtKB:Q96P63
UniProtKB:Q99574
UniProtKB:Q9TTE1
UniProtKB:Q9UIV8
WB:WBGene00005643

F

Seeded From UniProt

complete

involved_in

GO:0060512

prostate gland morphogenesis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70124
ensembl:ENSMUSP00000108350

P

Seeded From UniProt

complete

involved_in

GO:0050678

regulation of epithelial cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70124
ensembl:ENSMUSP00000108350

P

Seeded From UniProt

complete

involved_in

GO:0030198

extracellular matrix organization

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70124
ensembl:ENSMUSP00000108350

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70124
ensembl:ENSMUSP00000108350

C

Seeded From UniProt

complete

involved_in

GO:0002009

morphogenesis of an epithelium

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P70124
ensembl:ENSMUSP00000108350

P

Seeded From UniProt

complete

enables

GO:0004867

serine-type endopeptidase inhibitor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000240
InterPro:IPR033836

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000215

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0112

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Bailey, CM et al. (2005) Mammary serine protease inhibitor (Maspin) binds directly to interferon regulatory factor 6: identification of a novel serpin partnership. J. Biol. Chem. 280 34210-7 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page