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HUMAN:SP17

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) SPA17 (synonyms: SP17)
Protein Name(s) Sperm surface protein Sp17

Cancer/testis antigen 22 CT22 Sp17-1 Sperm autoantigenic protein 17 Sperm protein 17

External Links
UniProt Q15506
EMBL Z48570
AF334735
AF334810
AK311806
CH471065
BC032457
CCDS CCDS8450.1
PIR I38243
RefSeq NP_059121.1
UniGene Hs.286233
ProteinModelPortal Q15506
SMR Q15506
BioGrid 119741
IntAct Q15506
STRING 9606.ENSP00000227135
PhosphoSite Q15506
DMDM 2833264
MaxQB Q15506
PaxDb Q15506
PRIDE Q15506
DNASU 53340
Ensembl ENST00000227135
ENST00000532692
GeneID 53340
KEGG hsa:53340
UCSC uc001qap.3
CTD 53340
GeneCards GC11P124545
HGNC HGNC:11210
HPA HPA037568
MIM 608621
neXtProt NX_Q15506
PharmGKB PA36047
eggNOG NOG42033
GeneTree ENSGT00440000039164
HOGENOM HOG000059525
HOVERGEN HBG003879
InParanoid Q15506
OMA FKEQEPP
OrthoDB EOG7R2BHX
PhylomeDB Q15506
TreeFam TF332959
GeneWiki SPA17
GenomeRNAi 53340
NextBio 55970
PRO PR:Q15506
Proteomes UP000005640
Bgee Q15506
CleanEx HS_SPA17
Genevestigator Q15506
GO GO:0005737
GO:0016020
GO:0031514
GO:0072372
GO:0007339
GO:0003351
GO:0007338
GO:0007283
InterPro IPR003117
IPR000048
IPR012105
Pfam PF00612
PF02197
PIRSF PIRSF016533
SMART SM00015
SM00394
SUPFAM SSF47391
PROSITE PS50096

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0097228

sperm principal piece

PMID:15257753[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0035686

sperm fibrous sheath

PMID:19604394[2]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(CL:0000019)

Seeded From UniProt

complete

part_of

GO:0005929

cilium

PMID:18421703[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0031514

motile cilium

PMID:18421703[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:18421703[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0003351

epithelial cilium movement

PMID:18421703[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0097228

sperm principal piece

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1333778
PANTHER:PTN000075712
UniProtKB:Q15506

C

Seeded From UniProt

complete

part_of

GO:0035686

sperm fibrous sheath

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1333778
PANTHER:PTN000075712
UniProtKB:Q15506

C

Seeded From UniProt

complete

part_of

GO:0005929

cilium

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1333778
PANTHER:PTN000075712
UniProtKB:Q15506

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1333778
PANTHER:PTN000075712
UniProtKB:Q15506

C

Seeded From UniProt

complete

enables

GO:0005516

calmodulin binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0013467
MGI:MGI:1927184
PANTHER:PTN000075705
RGD:61833

F

Seeded From UniProt

complete

part_of

GO:0097228

sperm principal piece

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q62252
ensembl:ENSMUSP00000002013

C

Seeded From UniProt

complete

part_of

GO:0035686

sperm fibrous sheath

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q62252
ensembl:ENSMUSP00000002013

C

Seeded From UniProt

complete

part_of

GO:0009897

external side of plasma membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q62252
ensembl:ENSMUSP00000002013

C

Seeded From UniProt

complete

part_of

GO:0005929

cilium

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q62252
ensembl:ENSMUSP00000002013

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q62252
ensembl:ENSMUSP00000002013

C

Seeded From UniProt

complete

involved_in

GO:0007339

binding of sperm to zona pellucida

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012105

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012105

C

Seeded From UniProt

complete

involved_in

GO:0007338

single fertilization

PMID:8688458[5]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007283

spermatogenesis

PMID:8688458[5]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Lea, IA et al. (2004) Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella. Reprod. Biol. Endocrinol. 2 57 PubMed GONUTS page
  2. Chiriva-Internati, M et al. (2009) Sperm protein 17 is expressed in the sperm fibrous sheath. J Transl Med 7 61 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Newell, AE et al. (2008) Protein kinase A RII-like (R2D2) proteins exhibit differential localization and AKAP interaction. Cell Motil. Cytoskeleton 65 539-52 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 4.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  5. 5.0 5.1 Lea, IA et al. (1996) Cloning and sequencing of cDNAs encoding the human sperm protein, Sp17. Biochim. Biophys. Acta 1307 263-6 PubMed GONUTS page