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HUMAN:SG11B

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) SPAG11B (synonyms: EP2, HE2)
Protein Name(s) Sperm-associated antigen 11B

Human epididymis-specific protein 2 He2 Protein EP2 Sperm antigen HE2

External Links
UniProt Q08648
EMBL X67697
AF168616
AF168617
AY005129
AY005129
AY005129
AY005129
AY005129
AY005129
AJ628017
AJ635328
AC130360
CCDS CCDS47774.1
CCDS5966.1
CCDS5967.1
PIR I37454
RefSeq NP_057596.1
NP_478107.2
NP_478108.2
NP_478109.1
NP_478110.1
NP_478113.2
NP_478114.2
UniGene Hs.2717
ProteinModelPortal Q08648
IntAct Q08648
TCDB 1.C.85.1.5
DMDM 93141314
PRIDE Q08648
DNASU 10407
Ensembl ENST00000297498
ENST00000317900
ENST00000458665
ENST00000528168
ENST00000619134
ENST00000622314
GeneID 10407
KEGG hsa:10407
UCSC uc003wri.3
uc003wrk.3
uc003wrm.3
CTD 10407
GeneCards GC08M007294
HGNC HGNC:14534
MIM 606560
neXtProt NX_Q08648
PharmGKB PA37894
eggNOG NOG121990
GeneTree ENSGT00760000119452
HOVERGEN HBG073275
InParanoid Q08648
OMA CKKSEGY
PhylomeDB Q08648
ChiTaRS SPAG11B
GeneWiki SPAG11B
GenomeRNAi 10407
NextBio 39435
PRO PR:Q08648
Proteomes UP000005640
UP000005640
Bgee Q08648
ExpressionAtlas Q08648
Genevestigator Q08648
GO GO:0005576
GO:0007283
InterPro IPR007988
Pfam PF05324

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

part_of

GO:0005576

extracellular region

PMID:10698202[1]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003674

molecular_function

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0061844

antimicrobial humoral immune response mediated by antimicrobial peptide

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000362998
UniProtKB:Q08648

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007988

C

Seeded From UniProt

complete

involved_in

GO:0051715

cytolysis in other organism

PMID:16411022[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0061844

antimicrobial humoral immune response mediated by antimicrobial peptide

PMID:16411022[3]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007283

spermatogenesis

PMID:8167223[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0006952

defense response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0211

P

Seeded From UniProt

complete

involved_in

GO:0042742

defense response to bacterium

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0044

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Hamil, KG et al. (2000) HE2beta and HE2gamma, new members of an epididymis-specific family of androgen-regulated proteins in the human. Endocrinology 141 1245-53 PubMed GONUTS page
  2. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. 3.0 3.1 Yenugu, S et al. (2006) Antimicrobial actions of human and macaque sperm associated antigen (SPAG) 11 isoforms: influence of the N-terminal peptide. Mol. Cell. Biochem. 284 25-37 PubMed GONUTS page
  4. Osterhoff, C et al. (1994) Molecular cloning and characterization of a novel human sperm antigen (HE2) specifically expressed in the proximal epididymis. Biol. Reprod. 50 516-25 PubMed GONUTS page