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HUMAN:SCTM1
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | SECTM1 (synonyms: K12) | |
Protein Name(s) | Secreted and transmembrane protein 1
Protein K-12 | |
External Links | ||
UniProt | Q8WVN6 | |
EMBL | U77643 AK312980 CH471099 BC017716 | |
CCDS | CCDS11808.1 | |
RefSeq | NP_002995.1 XP_005256449.1 | |
UniGene | Hs.558009 | |
ProteinModelPortal | Q8WVN6 | |
BioGrid | 112298 | |
IntAct | Q8WVN6 | |
PhosphoSite | Q8WVN6 | |
DMDM | 25009245 | |
MaxQB | Q8WVN6 | |
PaxDb | Q8WVN6 | |
PeptideAtlas | Q8WVN6 | |
PRIDE | Q8WVN6 | |
DNASU | 6398 | |
Ensembl | ENST00000269389 | |
GeneID | 6398 | |
KEGG | hsa:6398 | |
UCSC | uc002keo.3 | |
CTD | 6398 | |
GeneCards | GC17M080278 | |
HGNC | HGNC:10707 | |
HPA | HPA051214 | |
MIM | 602602 | |
neXtProt | NX_Q8WVN6 | |
PharmGKB | PA35630 | |
eggNOG | NOG38953 | |
GeneTree | ENSGT00530000064499 | |
HOGENOM | HOG000231222 | |
HOVERGEN | HBG061092 | |
InParanoid | Q8WVN6 | |
OrthoDB | EOG71RXKJ | |
PhylomeDB | Q8WVN6 | |
TreeFam | TF336992 | |
ChiTaRS | SECTM1 | |
GeneWiki | SECTM1 | |
GenomeRNAi | 6398 | |
NextBio | 24856 | |
PRO | PR:Q8WVN6 | |
Proteomes | UP000005640 | |
Bgee | Q8WVN6 | |
CleanEx | HS_SECTM1 | |
ExpressionAtlas | Q8WVN6 | |
Genevestigator | Q8WVN6 | |
GO | GO:0005615 GO:0070062 GO:0005794 GO:0016021 GO:0005886 GO:0005125 GO:0004871 GO:0006955 GO:0007498 GO:0043123 GO:0007165 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0016021 |
integral to membrane |
ECO:0000314 |
C |
Fig.3C western blot detected K12 protein in the insoluble pellet fraction after treatment with sodium carbonate(pH 11.5) |
complete | |||||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001088) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB signaling |
ECO:0007001 |
high throughput mutant phenotypic evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000387964 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005125 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005125 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0005125 |
cytokine activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006955 |
immune response |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007498 |
mesoderm development |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006955 |
immune response |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005615 |
extracellular space |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005125 |
cytokine activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Slentz-Kesler, KA et al. (1998) Identification and characterization of K12 (SECTM1), a novel human gene that encodes a Golgi-associated protein with transmembrane and secreted isoforms. Genomics 47 327-40 PubMed GONUTS page
- ↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
- ↑ Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page
- ↑ Matsuda, A et al. (2003) Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene 22 3307-18 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page