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HUMAN:S26A5
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | SLC26A5 (synonyms: PRES) | |
Protein Name(s) | Prestin
Solute carrier family 26 member 5 | |
External Links | ||
UniProt | P58743 | |
EMBL | AF523354 AY256823 AY256824 AY256825 AY289134 AC004668 AC005064 AC093701 BC100833 | |
CCDS | CCDS43629.1 CCDS43630.1 CCDS55150.1 CCDS5732.1 CCDS5733.1 | |
RefSeq | NP_001161434.1 NP_945350.1 NP_996766.1 NP_996767.1 NP_996768.1 | |
UniGene | Hs.585146 | |
ProteinModelPortal | P58743 | |
SMR | P58743 | |
STRING | 9606.ENSP00000304783 | |
TCDB | 2.A.53.2.19 | |
PhosphoSite | P58743 | |
DMDM | 20139418 | |
PaxDb | P58743 | |
PRIDE | P58743 | |
Ensembl | ENST00000306312 ENST00000339444 ENST00000356767 ENST00000393723 ENST00000393730 ENST00000393735 ENST00000432958 | |
GeneID | 375611 | |
KEGG | hsa:375611 | |
UCSC | uc003vbt.2 uc003vbu.2 uc003vbv.2 uc003vbx.3 uc003vbz.3 | |
CTD | 375611 | |
GeneCards | GC07M102993 | |
HGNC | HGNC:9359 | |
MIM | 604943 613865 | |
neXtProt | NX_P58743 | |
Orphanet | 90636 | |
PharmGKB | PA33731 | |
eggNOG | COG0659 | |
GeneTree | ENSGT00760000119026 | |
HOGENOM | HOG000006546 | |
HOVERGEN | HBG000639 | |
InParanoid | P58743 | |
KO | K14703 | |
OrthoDB | EOG76T9QT | |
PhylomeDB | P58743 | |
TreeFam | TF313784 | |
GeneWiki | Prestin | |
GenomeRNAi | 375611 | |
NextBio | 100545 | |
PRO | PR:P58743 | |
Proteomes | UP000005640 | |
Bgee | P58743 | |
CleanEx | HS_SLC26A5 | |
ExpressionAtlas | P58743 | |
Genevestigator | P58743 | |
GO | GO:0016323 GO:0016021 GO:0016328 GO:0008271 GO:0008360 GO:0042391 GO:0007605 | |
Gene3D | 3.30.750.24 | |
InterPro | IPR030282 IPR018045 IPR002645 IPR001902 IPR030402 IPR011547 | |
PANTHER | PTHR11814 PTHR11814:SF32 | |
Pfam | PF01740 PF13792 PF00916 | |
SUPFAM | SSF52091 | |
TIGRFAMs | TIGR00815 | |
PROSITE | PS01130 PS50801 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0007605 |
sensory perception of sound |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0019531 |
oxalate transmembrane transporter activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0036770 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0015301 |
anion:anion antiporter activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:107181 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0015116 |
sulfate transmembrane transporter activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0036770 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0015108 |
chloride transmembrane transporter activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:107181 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0015106 |
bicarbonate transmembrane transporter activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0036770 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2159728 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0015701 |
bicarbonate transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015106 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0019532 |
oxalate transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0019531 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1902358 |
sulfate transmembrane transport |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0008271 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1902358 |
sulfate transmembrane transport |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0015116 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1902358 |
sulfate transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015116 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:2000147 |
positive regulation of cell motility |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1902476 |
chloride transmembrane transport |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1902074 |
response to salt |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0098656 |
anion transmembrane transport |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0097066 |
response to thyroid hormone |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090102 |
cochlea development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051262 |
protein tetramerization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045793 |
positive regulation of cell size |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042493 |
response to drug |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035864 |
response to potassium ion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034766 |
negative regulation of ion transmembrane transport |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0034220 |
ion transmembrane transport |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0016328 |
lateral plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0016323 |
basolateral plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0015755 |
fructose transmembrane transport |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010996 |
response to auditory stimulus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0009751 |
response to salicylic acid |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008134 |
transcription factor binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0002931 |
response to ischemia |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9EPH0 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042391 |
regulation of membrane potential |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99NH7 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0030507 |
spectrin binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99NH7 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0016328 |
lateral plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99NH7 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0016323 |
basolateral plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99NH7 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99NH7 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007605 |
sensory perception of sound |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0008271 |
secondary active sulfate transmembrane transporter activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008272 |
sulfate transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0015116 |
sulfate transmembrane transporter activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0055085 |
transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007605 |
sensory perception of sound |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008360 |
regulation of cell shape |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Liu, XZ et al. (2003) Prestin, a cochlear motor protein, is defective in non-syndromic hearing loss. Hum. Mol. Genet. 12 1155-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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- GO:0042391 ! regulation of membrane potential
- GO:0008360 ! regulation of cell shape
- GO:0010996 ! response to auditory stimulus
- GO:0002931 ! response to ischemia
- GO:0009751 ! response to salicylic acid
- GO:0035864 ! response to potassium ion
- GO:0042493 ! response to drug
- GO:0097066 ! response to thyroid hormone
- GO:1902074 ! response to salt
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