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HUMAN:ROBO4
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ROBO4 | |
| Protein Name(s) | Roundabout homolog 4
Magic roundabout | |
| External Links | ||
| UniProt | Q8WZ75 | |
| EMBL | AF361473 AY358083 AK000805 AK025195 AK027852 AK074163 AK289769 BC039602 BC064643 BC111562 BC111748 | |
| CCDS | CCDS8455.1 | |
| RefSeq | NP_001288017.1 NP_061928.4 | |
| UniGene | Hs.524121 | |
| ProteinModelPortal | Q8WZ75 | |
| SMR | Q8WZ75 | |
| BioGrid | 120025 | |
| IntAct | Q8WZ75 | |
| STRING | 9606.ENSP00000304945 | |
| MEROPS | I43.001 | |
| PhosphoSite | Q8WZ75 | |
| DMDM | 49036490 | |
| PaxDb | Q8WZ75 | |
| PRIDE | Q8WZ75 | |
| Ensembl | ENST00000306534 | |
| GeneID | 54538 | |
| KEGG | hsa:54538 | |
| UCSC | uc001qbg.3 uc001qbh.2 uc001qbi.3 | |
| CTD | 54538 | |
| GeneCards | GC11M124753 | |
| HGNC | HGNC:17985 | |
| MIM | 607528 | |
| neXtProt | NX_Q8WZ75 | |
| PharmGKB | PA34622 | |
| eggNOG | NOG325715 | |
| GeneTree | ENSGT00770000120606 | |
| HOVERGEN | HBG061836 | |
| InParanoid | Q8WZ75 | |
| KO | K06784 | |
| OMA | QILVHPQ | |
| OrthoDB | EOG7FFMR3 | |
| PhylomeDB | Q8WZ75 | |
| TreeFam | TF351053 | |
| GeneWiki | ROBO4 | |
| GenomeRNAi | 54538 | |
| NextBio | 56970 | |
| PRO | PR:Q8WZ75 | |
| Proteomes | UP000005640 | |
| Bgee | Q8WZ75 | |
| CleanEx | HS_ROBO4 | |
| ExpressionAtlas | Q8WZ75 | |
| Genevestigator | Q8WZ75 | |
| GO | GO:0009897 GO:0070062 GO:0016021 GO:0004872 GO:0001525 GO:0030154 GO:0030336 GO:0030334 | |
| Gene3D | 2.60.40.10 | |
| InterPro | IPR003961 IPR007110 IPR013783 IPR013098 IPR003598 | |
| Pfam | PF00041 PF07679 | |
| SMART | SM00060 SM00408 | |
| SUPFAM | SSF49265 | |
| PROSITE | PS50853 PS50835 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030334 |
regulation of cell migration |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001525 |
angiogenesis |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0098632 |
cell-cell adhesion mediator activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0010473 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0070593 |
dendrite self-avoidance |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0010473 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030424 |
axon |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104750 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007411 |
axon guidance |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0010473 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007156 |
homophilic cell adhesion via plasma membrane adhesion molecules |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000635 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000635 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0038023 |
signaling receptor activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001525 |
angiogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
- ↑ Seth, P et al. (2005) Magic roundabout, a tumor endothelial marker: expression and signaling. Biochem. Biophys. Res. Commun. 332 533-41 PubMed GONUTS page
- ↑ Bedell, VM et al. (2005) roundabout4 is essential for angiogenesis in vivo. Proc. Natl. Acad. Sci. U.S.A. 102 6373-8 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 5.0 5.1 Schmucker, D (2003) Downstream of guidance receptors: entering the baroque period of axon guidance signaling. Neuron 40 4-6 PubMed GONUTS page
