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HUMAN:RIMS4

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) RIMS4 (synonyms: C20orf190)
Protein Name(s) Regulating synaptic membrane exocytosis protein 4

RIM4 gamma Rab3-interacting molecule 4 RIM 4

External Links
UniProt Q9H426
EMBL AY326954
AL118522
CH471077
CH471077
BC104190
BC112985
CCDS CCDS13338.1
CCDS56191.1
RefSeq NP_001192246.1
NP_892015.1
UniGene Hs.517065
ProteinModelPortal Q9H426
SMR Q9H426
BioGrid 126676
IntAct Q9H426
STRING 9606.ENSP00000361942
PhosphoSite Q9H426
DMDM 41017798
PaxDb Q9H426
PRIDE Q9H426
DNASU 140730
Ensembl ENST00000372851
ENST00000541604
GeneID 140730
KEGG hsa:140730
UCSC uc002xms.3
uc010ggu.3
CTD 140730
GeneCards GC20M043380
HGNC HGNC:16183
HPA HPA060928
MIM 611601
neXtProt NX_Q9H426
PharmGKB PA25733
eggNOG NOG291389
GeneTree ENSGT00550000074588
HOGENOM HOG000231017
HOVERGEN HBG056381
InParanoid Q9H426
KO K15299
OMA GRMERKH
OrthoDB EOG7BGHJV
PhylomeDB Q9H426
SignaLink Q9H426
GenomeRNAi 140730
NextBio 84305
PRO PR:Q9H426
Proteomes UP000005640
Bgee Q9H426
CleanEx HS_RIMS4
ExpressionAtlas Q9H426
Genevestigator Q9H426
GO GO:0030054
GO:0048786
GO:0097060
GO:0044325
GO:0006887
GO:0006836
GO:0042391
GO:2000300
Gene3D 2.60.40.150
InterPro IPR000008
Pfam PF00168
SMART SM00239
SUPFAM SSF49562
PROSITE PS50004

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8CIX1

P

Seeded From UniProt

complete

part_of

GO:0097060

synaptic membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60191

C

Seeded From UniProt

complete

enables

GO:0044325

ion channel binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60191

F

Seeded From UniProt

complete

involved_in

GO:0042391

regulation of membrane potential

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P60191

P

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001741737
RGD:628695
RGD:628762

P

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000255280
RGD:628695
RGD:628762

P

Seeded From UniProt

complete

part_of

GO:0098831

presynaptic active zone cytoplasmic component

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
PANTHER:PTN000255280

C

Seeded From UniProt

complete

involved_in

GO:0050806

positive regulation of synaptic transmission

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000255280
WB:WBGene00006750

P

Seeded From UniProt

complete

involved_in

GO:0048791

calcium ion-regulated exocytosis of neurotransmitter

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
MGI:MGI:2152972
PANTHER:PTN001741737

P

Seeded From UniProt

complete

involved_in

GO:0048791

calcium ion-regulated exocytosis of neurotransmitter

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
MGI:MGI:2152972
PANTHER:PTN000255280

P

Seeded From UniProt

complete

part_of

GO:0048788

cytoskeleton of presynaptic active zone

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0264606
PANTHER:PTN000255280
UniProtKB:A0A0B4K6M2

C

Seeded From UniProt

complete

involved_in

GO:0048167

regulation of synaptic plasticity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000255280
UniProtKB:A0A0B4K6M2

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
PANTHER:PTN000255280
RGD:620001
WB:WBGene00006750

C

Seeded From UniProt

complete

enables

GO:0044325

ion channel binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
MGI:MGI:2152972
MGI:MGI:2443331
MGI:MGI:2674366
PANTHER:PTN000952366

F

Seeded From UniProt

complete

part_of

GO:0042734

presynaptic membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000255280
RGD:620000

C

Seeded From UniProt

complete

involved_in

GO:0042391

regulation of membrane potential

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
MGI:MGI:2152972
MGI:MGI:2443331
MGI:MGI:2674366
PANTHER:PTN001741737

P

Seeded From UniProt

complete

involved_in

GO:0042391

regulation of membrane potential

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
MGI:MGI:2152972
MGI:MGI:2443331
MGI:MGI:2674366
PANTHER:PTN000952366

P

Seeded From UniProt

complete

enables

GO:0017137

Rab GTPase binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000952366
RGD:620000
WB:WBGene00006750

F

Seeded From UniProt

complete

part_of

GO:0097060

synaptic membrane

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P60191
ensembl:ENSMUSP00000045637

C

Seeded From UniProt

complete

enables

GO:0044325

ion channel binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P60191
ensembl:ENSMUSP00000045637

F

Seeded From UniProt

complete

involved_in

GO:0042391

regulation of membrane potential

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P60191
ensembl:ENSMUSP00000045637

P

Seeded From UniProt

complete

involved_in

GO:0006887

exocytosis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039032

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039032

C

Seeded From UniProt

complete

enables

GO:0017137

Rab GTPase binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039032

F

Seeded From UniProt

complete

part_of

GO:0048786

presynaptic active zone

PMID:15217342[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006887

exocytosis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0268

P

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770
UniProtKB-SubCell:SL-0258

C

Seeded From UniProt

complete

involved_in

GO:0006836

neurotransmitter transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0532

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Sudhof, TC (2004) The synaptic vesicle cycle. Annu. Rev. Neurosci. 27 509-47 PubMed GONUTS page