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HUMAN:RIMS3

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) RIMS3 (synonyms: KIAA0237)
Protein Name(s) Regulating synaptic membrane exocytosis protein 3

Nim3 RIM3 gamma Rab-3-interacting molecule 3 RIM 3

External Links
UniProt Q9UJD0
EMBL AY326956
KJ535026
D87074
AL031289
CH471059
CH471059
BC003103
CCDS CCDS30687.1
RefSeq NP_055562.2
UniGene Hs.654808
ProteinModelPortal Q9UJD0
SMR Q9UJD0
BioGrid 115127
IntAct Q9UJD0
PhosphoSite Q9UJD0
DMDM 41017811
MaxQB Q9UJD0
PaxDb Q9UJD0
PeptideAtlas Q9UJD0
PRIDE Q9UJD0
DNASU 9783
Ensembl ENST00000372683
ENST00000372684
GeneID 9783
KEGG hsa:9783
UCSC uc001cfu.1
CTD 9783
GeneCards GC01M041086
HGNC HGNC:21292
HPA HPA024172
MIM 611600
neXtProt NX_Q9UJD0
PharmGKB PA134980870
eggNOG NOG316742
GeneTree ENSGT00550000074588
HOGENOM HOG000231017
HOVERGEN HBG056381
InParanoid Q9UJD0
KO K15298
OMA GPESQFS
OrthoDB EOG7BGHJV
PhylomeDB Q9UJD0
TreeFam TF315600
ChiTaRS RIMS3
GenomeRNAi 9783
NextBio 36838
PRO PR:Q9UJD0
Proteomes UP000005640
Bgee Q9UJD0
CleanEx HS_RIMS3
Genevestigator Q9UJD0
GO GO:0030054
GO:0048786
GO:0044325
GO:0017156
GO:0006836
GO:0042391
GO:2000300
Gene3D 2.60.40.150
InterPro IPR000008
Pfam PF00168
SMART SM00239
SUPFAM SSF49562
PROSITE PS50004

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0017156

calcium ion regulated exocytosis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9JIR3

P

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9JIR3

P

Seeded From UniProt

complete

enables

GO:0044325

ion channel binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q80U57

F

Seeded From UniProt

complete

involved_in

GO:0042391

regulation of membrane potential

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q80U57

P

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001741737
RGD:628695
RGD:628762

P

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000255280
RGD:628695
RGD:628762

P

Seeded From UniProt

complete

part_of

GO:0098831

presynaptic active zone cytoplasmic component

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
PANTHER:PTN000255280

C

Seeded From UniProt

complete

involved_in

GO:0050806

positive regulation of synaptic transmission

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000255280
WB:WBGene00006750

P

Seeded From UniProt

complete

involved_in

GO:0048791

calcium ion-regulated exocytosis of neurotransmitter

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
MGI:MGI:2152972
PANTHER:PTN001741737

P

Seeded From UniProt

complete

involved_in

GO:0048791

calcium ion-regulated exocytosis of neurotransmitter

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
MGI:MGI:2152972
PANTHER:PTN000255280

P

Seeded From UniProt

complete

part_of

GO:0048788

cytoskeleton of presynaptic active zone

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0264606
PANTHER:PTN000255280
UniProtKB:A0A0B4K6M2

C

Seeded From UniProt

complete

involved_in

GO:0048167

regulation of synaptic plasticity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000255280
UniProtKB:A0A0B4K6M2

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
PANTHER:PTN000255280
RGD:620001
WB:WBGene00006750

C

Seeded From UniProt

complete

enables

GO:0044325

ion channel binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
MGI:MGI:2152972
MGI:MGI:2443331
MGI:MGI:2674366
PANTHER:PTN000952366

F

Seeded From UniProt

complete

part_of

GO:0042734

presynaptic membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000255280
RGD:620000

C

Seeded From UniProt

complete

involved_in

GO:0042391

regulation of membrane potential

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
MGI:MGI:2152972
MGI:MGI:2443331
MGI:MGI:2674366
PANTHER:PTN001741737

P

Seeded From UniProt

complete

involved_in

GO:0042391

regulation of membrane potential

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:2152971
MGI:MGI:2152972
MGI:MGI:2443331
MGI:MGI:2674366
PANTHER:PTN000952366

P

Seeded From UniProt

complete

enables

GO:0017137

Rab GTPase binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000952366
RGD:620000
WB:WBGene00006750

F

Seeded From UniProt

complete

enables

GO:0044325

ion channel binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80U57
ensembl:ENSMUSP00000068178

F

Seeded From UniProt

complete

involved_in

GO:0042391

regulation of membrane potential

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q80U57
ensembl:ENSMUSP00000068178

P

Seeded From UniProt

complete

involved_in

GO:0006887

exocytosis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039032

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039032

C

Seeded From UniProt

complete

enables

GO:0017137

Rab GTPase binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039032

F

Seeded From UniProt

complete

part_of

GO:0048786

presynaptic active zone

PMID:15217342[2]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006887

exocytosis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0268

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770
UniProtKB-SubCell:SL-0258

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

involved_in

GO:0006836

neurotransmitter transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0532

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Sudhof, TC (2004) The synaptic vesicle cycle. Annu. Rev. Neurosci. 27 509-47 PubMed GONUTS page