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HUMAN:RFIP5

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) RAB11FIP5 (synonyms: GAF1, KIAA0857, RIP11)
Protein Name(s) Rab11 family-interacting protein 5

Rab11-FIP5 Gamma-SNAP-associated factor 1 Gaf-1 Phosphoprotein pp75 Rab11-interacting protein Rip11

External Links
UniProt Q9BXF6
EMBL AF334812
AB020664
BC035013
AF153085
CCDS CCDS1923.1
PIR T17312
RefSeq NP_056285.1
UniGene Hs.24557
ProteinModelPortal Q9BXF6
SMR Q9BXF6
BioGrid 117518
IntAct Q9BXF6
STRING 9606.ENSP00000258098
PhosphoSite Q9BXF6
DMDM 34223002
MaxQB Q9BXF6
PaxDb Q9BXF6
PRIDE Q9BXF6
DNASU 26056
Ensembl ENST00000258098
GeneID 26056
KEGG hsa:26056
UCSC uc002sit.4
CTD 26056
GeneCards GC02M073212
HGNC HGNC:24845
HPA HPA036406
HPA036407
MIM 605536
neXtProt NX_Q9BXF6
PharmGKB PA134971129
eggNOG NOG84049
GeneTree ENSGT00530000063203
HOGENOM HOG000234700
HOVERGEN HBG079127
InParanoid Q9BXF6
KO K12484
OMA VEKTHGC
OrthoDB EOG7WQ7SB
PhylomeDB Q9BXF6
TreeFam TF326172
GeneWiki RAB11FIP5
GenomeRNAi 26056
NextBio 47930
PRO PR:Q9BXF6
Proteomes UP000005640
Bgee Q9BXF6
CleanEx HS_RAB11FIP5
ExpressionAtlas Q9BXF6
Genevestigator Q9BXF6
GO GO:0005769
GO:0031901
GO:0005794
GO:0000139
GO:0043231
GO:0005815
GO:0005741
GO:0055037
GO:0055038
GO:0030141
GO:0030658
GO:0043015
GO:0071468
GO:0035773
GO:0015031
GO:0045055
GO:2000008
Gene3D 2.60.40.150
InterPro IPR000008
IPR019018
Pfam PF00168
PF09457
SMART SM00239
SUPFAM SSF49562
PROSITE PS50004
PS51511

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0070164

negative regulation of adiponectin secretion

PMID:24040321[1]

ECO:0000314

P

Figure 1A

complete
CACAO 8902

involved_in

GO:0070164

negative regulation of adiponectin secretion

PMID:24040321[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000008

regulation of protein localization to cell surface

PMID:20717956[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071468

cellular response to acidic pH

PMID:20717956[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0055037

recycling endosome

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8R361

C

Seeded From UniProt

complete

involved_in

GO:0045055

regulated exocytosis

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8R361

P

Seeded From UniProt

complete

enables

GO:0043015

gamma-tubulin binding

PMID:11278501[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0035773

insulin secretion involved in cellular response to glucose stimulus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8R361

P

Seeded From UniProt

complete

part_of

GO:0030141

secretory granule

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8R361

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8R361

C

Seeded From UniProt

complete

part_of

GO:0005769

early endosome

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8R361

C

Seeded From UniProt

complete

part_of

GO:0005741

mitochondrial outer membrane

PMID:11278501[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0045055

regulated exocytosis

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1098586
MGI:MGI:1922248
PANTHER:PTN000405433

P

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000405433
UniProtKB:Q6WKZ4
UniProtKB:Q7L804
UniProtKB:Q9BXF6

C

Seeded From UniProt

complete

enables

GO:0017137

Rab GTPase binding

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0027335
PANTHER:PTN000405433

F

Seeded From UniProt

complete

part_of

GO:0005769

early endosome

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1098586
PANTHER:PTN000405438

C

Seeded From UniProt

complete

part_of

GO:0043231

intracellular membrane-bounded organelle

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005815

microtubule organizing center

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0017137

Rab GTPase binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR037789

F

Seeded From UniProt

complete

part_of

GO:0031410

cytoplasmic vesicle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0968

C

Seeded From UniProt

complete

part_of

GO:0005768

endosome

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0967

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0015031

protein transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0653

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496

C

Seeded From UniProt

complete

part_of

GO:0005794

Golgi apparatus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0333

C

Seeded From UniProt

complete

part_of

GO:0030658

transport vesicle membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0245

C

Seeded From UniProt

complete

part_of

GO:0031966

mitochondrial membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0171

C

Seeded From UniProt

complete

part_of

GO:0000139

Golgi membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0134

C

Seeded From UniProt

complete

part_of

GO:0031901

early endosome membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0093

C

Seeded From UniProt

complete

part_of

GO:0055038

recycling endosome membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0231

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Carson, BP et al. (2013) The rab11 effector protein FIP1 regulates adiponectin trafficking and secretion. PLoS ONE 8 e74687 PubMed GONUTS page
  2. 2.0 2.1 Oehlke, O et al. (2011) Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts. J. Cell. Physiol. 226 638-51 PubMed GONUTS page
  3. 3.0 3.1 Chen, D et al. (2001) Gaf-1, a gamma -SNAP-binding protein associated with the mitochondria. J. Biol. Chem. 276 13127-35 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page