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HUMAN:RASA2
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | RASA2 (synonyms: GAP1M, RASGAP) | |
| Protein Name(s) | Ras GTPase-activating protein 2
GTPase-activating protein 1m GAP1m | |
| External Links | ||
| UniProt | Q15283 | |
| EMBL | D78155 D78156 D82880 D82881 AF115573 AC010184 AC092977 CH471052 AK292016 | |
| CCDS | CCDS3117.1 | |
| PIR | JC5047 | |
| RefSeq | NP_001290174.1 NP_001290175.1 NP_006497.2 | |
| UniGene | Hs.655941 Hs.98445 | |
| ProteinModelPortal | Q15283 | |
| SMR | Q15283 | |
| BioGrid | 111857 | |
| STRING | 9606.ENSP00000286364 | |
| iPTMnet | Q15283 | |
| PhosphoSite | Q15283 | |
| BioMuta | RASA2 | |
| DMDM | 519668674 | |
| MaxQB | Q15283 | |
| PaxDb | Q15283 | |
| PRIDE | Q15283 | |
| DNASU | 5922 | |
| Ensembl | ENST00000286364 | |
| GeneID | 5922 | |
| KEGG | hsa:5922 | |
| UCSC | uc003etz.1 uc003eua.1 | |
| CTD | 5922 | |
| GeneCards | RASA2 | |
| HGNC | HGNC:9872 | |
| HPA | HPA035374 HPA035375 | |
| MalaCards | RASA2 | |
| MIM | 601589 | |
| neXtProt | NX_Q15283 | |
| Orphanet | 648 | |
| PharmGKB | PA34233 | |
| eggNOG | KOG2059 ENOG410Y128 | |
| GeneTree | ENSGT00760000119092 | |
| HOGENOM | HOG000007183 | |
| HOVERGEN | HBG055643 | |
| InParanoid | Q15283 | |
| KO | K08053 | |
| OrthoDB | EOG7J17Z6 | |
| PhylomeDB | Q15283 | |
| TreeFam | TF105302 | |
| Reactome | R-HSA-5658442 | |
| ChiTaRS | RASA2 | |
| GenomeRNAi | 5922 | |
| NextBio | 23062 | |
| PRO | PR:Q15283 | |
| Proteomes | UP000005640 | |
| Bgee | Q15283 | |
| CleanEx | HS_RASA2 | |
| ExpressionAtlas | Q15283 | |
| Genevisible | Q15283 | |
| GO | GO:0005737 GO:0005829 GO:0031235 GO:0048471 GO:0005096 GO:0046872 GO:0000186 GO:0007411 GO:0007173 GO:0038095 GO:0008543 GO:0045087 GO:0008286 GO:0000165 GO:0046580 GO:0048011 GO:0043547 GO:0007265 GO:0007165 GO:0007264 GO:0048010 | |
| Gene3D | 1.10.506.10 2.30.29.30 2.60.40.150 | |
| InterPro | IPR000008 IPR011993 IPR001849 IPR023152 IPR001936 IPR008936 IPR001562 | |
| Pfam | PF00779 PF00168 PF00169 PF00616 | |
| PRINTS | PR00402 | |
| SMART | SM00107 SM00239 SM00233 SM00323 | |
| SUPFAM | SSF48350 SSF49562 SSF50729 | |
| PROSITE | PS50004 PS50003 PS00509 PS50018 PS51113 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0043547 |
positive regulation of GTPase activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005096 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043547 |
positive regulation of GTPase activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005096 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043547 |
positive regulation of GTPase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005096 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043547 |
positive regulation of GTPase activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005096 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005096 |
GTPase activator activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q63713 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005096 |
GTPase activator activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005543 |
phospholipid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035556 |
intracellular signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0043087 |
regulation of GTPase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046580 |
negative regulation of Ras protein signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007165 |
signal transduction |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005096 |
GTPase activator activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-6802834 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0000165 |
MAPK cascade |
Reactome:R-HSA-5673001 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005096 |
GTPase activator activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0048471 |
perinuclear region of cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Li, S et al. (1996) cDNA cloning and chromosomal mapping of a novel human GAP (GAP1M), a GTPase-activating protein of Ras. Genomics 35 625-7 PubMed GONUTS page
- ↑ Hattori, S & Baba, H (1996) [Heterogeneity of GTPase-activating proteins for Ras in the regulation of Ras signal transduction pathway]. Yakugaku Zasshi 116 21-38 PubMed GONUTS page