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HUMAN:Q6NVY4

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) BNIP3 (ECO:0000313 with EMBL:AAH67818.1)
Protein Name(s) BNIP3 protein (ECO:0000313 with EMBL:AAH67818.1)
External Links
UniProt Q6NVY4
EMBL BC067818
UniGene Hs.144873
HOGENOM HOG000232139
HOVERGEN HBG050707
Bgee Q6NVY4
ExpressionAtlas Q6NVY4
GO GO:0030425
GO:0016021
GO:0005740
GO:0005654
GO:0048102
GO:0050873
GO:0070301
GO:0097193
GO:0051402
GO:0043065
GO:0055093
GO:0001666
InterPro IPR010548
Pfam PF06553

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006914

autophagy

PMID:23142642[1]

ECO:0000314

P

Confirmed with a MYTH screen of human adult brain cDNA library, Table 1 shows the protein function of BNIP3 in autophagy and apoptosis.

complete
CACAO 5765

GO:0000975

regulatory region DNA binding

PMID:23579274[2]

ECO:0000314

F

Figure 3 shows how the protein binds to DNA at a specific region in the DR5 promoter, through oligo binding and Western blots

complete
CACAO 7960

part_of

GO:0005740

mitochondrial envelope

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010548

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010548

C

Seeded From UniProt

complete

involved_in

GO:0043065

positive regulation of apoptotic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010548

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Passantino, R et al. (2013) Identifying protein partners of CLN8, an ER-resident protein involved in neuronal ceroid lipofuscinosis. Biochim. Biophys. Acta 1833 529-40 PubMed GONUTS page
  2. Burton, TR et al. (2013) BNIP3 acts as transcriptional repressor of death receptor-5 expression and prevents TRAIL-induced cell death in gliomas. Cell Death Dis 4 e587 PubMed GONUTS page