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HUMAN:PIGEH
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | GSAP (synonyms: PION) | |
| Protein Name(s) | Gamma-secretase-activating protein
GSAP Protein pigeon homolog Gamma-secretase-activating protein 16 kDa C-terminal form GSAP-16K | |
| External Links | ||
| UniProt | A4D1B5 | |
| EMBL | AC004921 AC073635 CH236949 CH236949 CH471091 BC101499 AL834358 AL079277 AL079297 | |
| CCDS | CCDS34672.2 | |
| RefSeq | NP_059135.2 | |
| UniGene | Hs.186649 | |
| ProteinModelPortal | A4D1B5 | |
| DIP | DIP-59240N | |
| STRING | 9606.ENSP00000257626 | |
| PhosphoSite | A4D1B5 | |
| MaxQB | A4D1B5 | |
| PaxDb | A4D1B5 | |
| PRIDE | A4D1B5 | |
| Ensembl | ENST00000257626 | |
| GeneID | 54103 | |
| KEGG | hsa:54103 | |
| UCSC | uc003ugd.3 uc003ugf.3 uc003ugg.1 | |
| CTD | 54103 | |
| GeneCards | GC07M076941 | |
| H-InvDB | HIX0006796 | |
| HGNC | HGNC:28042 | |
| HPA | HPA020058 HPA023994 | |
| MIM | 613552 | |
| neXtProt | NX_A4D1B5 | |
| PharmGKB | PA164724500 | |
| eggNOG | NOG128840 | |
| GeneTree | ENSGT00390000012875 | |
| HOVERGEN | HBG095500 | |
| InParanoid | A4D1B5 | |
| OMA | FNLMFEA | |
| OrthoDB | EOG767391 | |
| PhylomeDB | A4D1B5 | |
| TreeFam | TF323853 | |
| GeneWiki | Protein_pigeon_homolog | |
| GenomeRNAi | 54103 | |
| NextBio | 56462 | |
| PRO | PR:A4D1B5 | |
| Proteomes | UP000005640 | |
| Bgee | A4D1B5 | |
| CleanEx | HS_PION | |
| ExpressionAtlas | A4D1B5 | |
| Genevestigator | A4D1B5 | |
| GO | GO:0005802 GO:0001540 GO:1902004 GO:0030162 | |
| InterPro | IPR028010 IPR026172 | |
| PANTHER | PTHR13630 | |
| Pfam | PF14959 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0034205 |
beta-amyloid formation |
ECO:0000315 |
P |
Figure 2 - transfection of cells with GSAP siRNA reduced the concentration of amyloid beta. Additionally, recombinant GSAP stimulated amyloid beta production in E. Coli. |
complete | |||||
|
involved_in |
GO:1902004 |
positive regulation of amyloid-beta formation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030162 |
regulation of proteolysis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005802 |
trans-Golgi network |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0001540 |
amyloid-beta binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1902004 |
positive regulation of amyloid-beta formation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q3TCV3 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
