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HUMAN:OSMR
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | OSMR (synonyms: OSMRB) | |
| Protein Name(s) | Oncostatin-M-specific receptor subunit beta
Interleukin-31 receptor subunit beta IL-31 receptor subunit beta IL-31R subunit beta IL-31R-beta IL-31RB | |
| External Links | ||
| UniProt | Q99650 | |
| EMBL | U60805 BC010943 BC063468 BC125209 BC125210 | |
| CCDS | CCDS3928.1 CCDS54847.1 | |
| RefSeq | NP_001161827.1 NP_003990.1 | |
| UniGene | Hs.120658 Hs.658389 | |
| ProteinModelPortal | Q99650 | |
| SMR | Q99650 | |
| BioGrid | 114617 | |
| IntAct | Q99650 | |
| MINT | MINT-4537651 | |
| STRING | 9606.ENSP00000274276 | |
| PhosphoSite | Q99650 | |
| DMDM | 74724833 | |
| MaxQB | Q99650 | |
| PaxDb | Q99650 | |
| PRIDE | Q99650 | |
| Ensembl | ENST00000274276 ENST00000502536 | |
| GeneID | 9180 | |
| KEGG | hsa:9180 | |
| UCSC | uc003jlm.2 uc003jln.2 | |
| CTD | 9180 | |
| GeneCards | GC05P038845 | |
| HGNC | HGNC:8507 | |
| HPA | HPA017278 | |
| MIM | 105250 601743 | |
| neXtProt | NX_Q99650 | |
| Orphanet | 353220 | |
| PharmGKB | PA32837 | |
| eggNOG | NOG43445 | |
| GeneTree | ENSGT00550000074436 | |
| HOGENOM | HOG000115294 | |
| HOVERGEN | HBG082088 | |
| InParanoid | Q99650 | |
| KO | K05057 | |
| OMA | YHQELKM | |
| OrthoDB | EOG7V49XP | |
| PhylomeDB | Q99650 | |
| TreeFam | TF338122 | |
| SignaLink | Q99650 | |
| ChiTaRS | OSMR | |
| GeneWiki | Oncostatin_M_receptor | |
| GenomeRNAi | 9180 | |
| NextBio | 34417 | |
| PRO | PR:Q99650 | |
| Proteomes | UP000005640 | |
| Bgee | Q99650 | |
| CleanEx | HS_OSMR | |
| ExpressionAtlas | Q99650 | |
| Genevestigator | Q99650 | |
| GO | GO:0005900 GO:0019838 GO:0004924 GO:0038165 GO:0002675 GO:0008284 GO:0034097 | |
| Gene3D | 2.60.40.10 | |
| InterPro | IPR003961 IPR003529 IPR013783 | |
| Pfam | PF00041 | |
| SMART | SM00060 | |
| SUPFAM | SSF49265 | |
| PROSITE | PS50853 PS01353 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0016324 |
apical plasma membrane |
ECO:0000314 |
C |
Figure 5 - OsMRβ normally in the apical membrane |
complete | |||||
|
part_of |
GO:0016324 |
apical plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0038165 |
oncostatin-M-mediated signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034097 |
response to cytokine |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019838 |
growth factor binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008284 |
positive regulation of cell population proliferation |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
Missing: with/from | |||
|
part_of |
GO:0005900 |
oncostatin-M receptor complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
contributes_to |
GO:0004924 |
oncostatin-M receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0002675 |
positive regulation of acute inflammatory response |
ECO:0000305 |
curator inference used in manual assertion |
GO:0034097 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004896 |
cytokine receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002745476 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043235 |
receptor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002745476 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019955 |
cytokine binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104579 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0009897 |
external side of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104579 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0008284 |
positive regulation of cell population proliferation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:96788 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005900 |
oncostatin-M receptor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002507073 |
C |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0004924 |
oncostatin-M receptor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1330819 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004896 |
cytokine receptor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019221 |
cytokine-mediated signaling pathway |
Reactome:R-HSA-6783589 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-HSA-6784204 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Li, R et al. (2011) CNTF mediates neurotrophic factor secretion and fluid absorption in human retinal pigment epithelium. PLoS ONE 6 e23148 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Mosley, B et al. (1996) Dual oncostatin M (OSM) receptors. Cloning and characterization of an alternative signaling subunit conferring OSM-specific receptor activation. J. Biol. Chem. 271 32635-43 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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