HUMAN:ORML3

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	ORMDL3
Protein Name(s)	ORM1-like protein 3
External Links
UniProt	Q8N138
EMBL	AF395708 AF373101 AF373102 AK074811 AY357943 AK075212 AK093063 CH471152 BC017087 BC071833
CCDS	CCDS11355.1
RefSeq	NP_644809.1 XP_005257884.1
UniGene	Hs.514151
ProteinModelPortal	Q8N138
BioGrid	125114
DIP	DIP-48687N
IntAct	Q8N138
MINT	MINT-1390099
STRING	9606.ENSP00000304858
PhosphoSite	Q8N138
DMDM	74728486
MaxQB	Q8N138
PaxDb	Q8N138
PRIDE	Q8N138
DNASU	94103
Ensembl	ENST00000304046 ENST00000394169 ENST00000579695 ENST00000584220
GeneID	94103
KEGG	hsa:94103
UCSC	uc002htj.2
CTD	94103
GeneCards	GC17M038077
HGNC	HGNC:16038
MIM	600807 610075
neXtProt	NX_Q8N138
PharmGKB	PA32821
eggNOG	COG5081
GeneTree	ENSGT00390000015817
HOGENOM	HOG000192741
HOVERGEN	HBG080033
InParanoid	Q8N138
OMA	IDNGAQY
OrthoDB	EOG7N8ZX8
PhylomeDB	Q8N138
TreeFam	TF323369
ChiTaRS	ORMDL3
GenomeRNAi	94103
NextBio	78379
PRO	PR:Q8N138
Proteomes	UP000005640
Bgee	Q8N138
CleanEx	HS_ORMDL3
ExpressionAtlas	Q8N138
Genevestigator	Q8N138
GO	GO:0005783 GO:0005789 GO:0016021 GO:0035339 GO:0006672
InterPro	IPR007203 IPR029883
PANTHER	PTHR12665 PTHR12665:SF11
Pfam	PF04061
PIRSF	PIRSF018147

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0035339	SPOTS complex	PMID:20182505	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006672	ceramide metabolic process	PMID:20182505	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	PMID:12093374	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1900060	negative regulation of ceramide biosynthetic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1913862 PANTHER:PTN000292374 UniProtKB:Q53FV1 UniProtKB:Q8N138 UniProtKB:Q9P0S3	P		Seeded From UniProt	complete
involved_in	GO:0090156	cellular sphingolipid homeostasis		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000292374 SGD:S000003270 SGD:S000004342 TAIR:locus:2035352 UniProtKB:Q9FHY3	P		Seeded From UniProt	complete
part_of	GO:0035339	SPOTS complex		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000292374 SGD:S000003270 SGD:S000004342 UniProtKB:Q8N138	C		Seeded From UniProt	complete
involved_in	GO:0006672	ceramide metabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000292374 UniProtKB:Q53FV1 UniProtKB:Q8N138 UniProtKB:Q9P0S3	P		Seeded From UniProt	complete
involved_in	GO:1900060	negative regulation of ceramide biosynthetic process		ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0035339	SPOTS complex		ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1900060	negative regulation of ceramide biosynthetic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9CPZ6 ensembl:ENSMUSP00000053056	P		Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007203 InterPro:IPR029883	C		Seeded From UniProt	complete
involved_in	GO:0006672	ceramide metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR029883	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007203	C		Seeded From UniProt	complete
involved_in	GO:0090156	cellular sphingolipid homeostasis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR029883	P		Seeded From UniProt	complete
involved_in	GO:0043312	neutrophil degranulation	Reactome:R-HSA-6798695	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0035579	specific granule membrane	Reactome:R-HSA-6799350	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030667	secretory granule membrane	Reactome:R-HSA-6798743	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-6799350 Reactome:R-HSA-6798743	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0256	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0097	C		Seeded From UniProt	complete
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References

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