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HUMAN:NKD1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | NKD1 (synonyms: NKD) | |
| Protein Name(s) | Protein naked cuticle homolog 1
Naked-1 hNkd hNkd1 | |
| External Links | ||
| UniProt | Q969G9 | |
| EMBL | AF358135 AB062886 AY061883 AF289584 AK314930 CH471092 BC051288 | |
| CCDS | CCDS10743.1 | |
| RefSeq | NP_149110.1 | |
| UniGene | Hs.187578 | |
| ProteinModelPortal | Q969G9 | |
| IntAct | Q969G9 | |
| STRING | 9606.ENSP00000268459 | |
| PhosphoSite | Q969G9 | |
| DMDM | 74731040 | |
| MaxQB | Q969G9 | |
| PaxDb | Q969G9 | |
| PRIDE | Q969G9 | |
| DNASU | 85407 | |
| Ensembl | ENST00000268459 | |
| GeneID | 85407 | |
| KEGG | hsa:85407 | |
| UCSC | uc002egg.2 | |
| CTD | 85407 | |
| GeneCards | GC16P050582 | |
| H-InvDB | HIX0027004 | |
| HGNC | HGNC:17045 | |
| HPA | HPA041352 HPA049413 | |
| MIM | 607851 | |
| neXtProt | NX_Q969G9 | |
| PharmGKB | PA31637 | |
| eggNOG | NOG47986 | |
| GeneTree | ENSGT00440000033589 | |
| HOGENOM | HOG000005649 | |
| HOVERGEN | HBG099718 | |
| InParanoid | Q969G9 | |
| KO | K03213 | |
| OMA | LGHKKHK | |
| OrthoDB | EOG75F4D6 | |
| PhylomeDB | Q969G9 | |
| TreeFam | TF328786 | |
| SignaLink | Q969G9 | |
| ChiTaRS | NKD1 | |
| GenomeRNAi | 85407 | |
| NextBio | 75970 | |
| PRO | PR:Q969G9 | |
| Proteomes | UP000005640 | |
| Bgee | Q969G9 | |
| CleanEx | HS_NKD1 | |
| Genevestigator | Q969G9 | |
| GO | GO:0005737 GO:0005886 GO:0005509 GO:0001754 GO:0090090 GO:1901233 GO:1901231 GO:0045732 GO:2000096 GO:0090249 GO:0007525 GO:0016055 | |
| Gene3D | 1.10.238.10 | |
| InterPro | IPR011992 IPR018247 IPR002048 | |
| PROSITE | PS00018 PS50222 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:2000096 |
positive regulation of Wnt signaling pathway, planar cell polarity pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901233 |
negative regulation of convergent extension involved in axis elongation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901231 |
positive regulation of non-canonical Wnt signaling pathway via JNK cascade |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090249 |
regulation of cell motility involved in somitogenic axis elongation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090090 |
negative regulation of canonical Wnt signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0090090 |
negative regulation of canonical Wnt signaling pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045732 |
positive regulation of protein catabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_regulation_target:(UniProtKB:P51141) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007525 |
somatic muscle development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001754 |
eye photoreceptor cell differentiation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000159 |
protein phosphatase type 2A complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030178 |
negative regulation of Wnt signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2135954 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002945 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:2000096 |
positive regulation of Wnt signaling pathway, planar cell polarity pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99MH6 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1901233 |
negative regulation of convergent extension involved in axis elongation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99MH6 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:1901231 |
positive regulation of non-canonical Wnt signaling pathway via JNK cascade |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99MH6 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0090090 |
negative regulation of canonical Wnt signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99MH6 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030178 |
negative regulation of Wnt signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99MH6 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0030165 |
PDZ domain binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99MH6 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005509 |
calcium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030178 |
negative regulation of Wnt signaling pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016055 |
Wnt signaling pathway |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Creyghton, MP et al. (2005) PR72, a novel regulator of Wnt signaling required for Naked cuticle function. Genes Dev. 19 376-86 PubMed GONUTS page
- ↑ 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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