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HUMAN:MYO10

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) MYO10 (synonyms: KIAA0799)
Protein Name(s) Unconventional myosin-X

Unconventional myosin-10

External Links
UniProt Q9HD67
EMBL AF247457
AF234532
AF132021
AF132022
AB018342
AC010310
AC010607
AC024588
BC041694
BC050682
BC108736
BC137168
BC150285
AI878891
AF184153
CCDS CCDS54834.1
PIR A59267
RefSeq NP_036466.2
XP_005248364.1
UniGene Hs.481720
PDB 2LW9
3AU4
3AU5
3PZD
PDBsum 2LW9
3AU4
3AU5
3PZD
ProteinModelPortal Q9HD67
SMR Q9HD67
BioGrid 110735
DIP DIP-46151N
IntAct Q9HD67
MINT MINT-1411122
STRING 9606.ENSP00000391106
PhosphoSite Q9HD67
DMDM 205371854
MaxQB Q9HD67
PaxDb Q9HD67
PRIDE Q9HD67
Ensembl ENST00000507288
ENST00000513610
GeneID 4651
KEGG hsa:4651
UCSC uc003jft.4
uc003jfv.2
CTD 4651
GeneCards GC05M016662
H-InvDB HIX0021772
HIX0164320
HGNC HGNC:7593
HPA CAB015224
HPA024223
MIM 601481
neXtProt NX_Q9HD67
PharmGKB PA31394
eggNOG COG5022
GeneTree ENSGT00770000120520
HOGENOM HOG000007044
HOVERGEN HBG052553
InParanoid Q9HD67
KO K12559
OMA DKGYTTL
OrthoDB EOG7Q5HC9
PhylomeDB Q9HD67
TreeFam TF316834
Reactome REACT_160086
REACT_22237
ChiTaRS MYO10
EvolutionaryTrace Q9HD67
GeneWiki MYO10
GenomeRNAi 4651
NextBio 17932
PRO PR:Q9HD67
Proteomes UP000005640
Bgee Q9HD67
CleanEx HS_MYO10
ExpressionAtlas Q9HD67
Genevestigator Q9HD67
GO GO:0005938
GO:0005737
GO:0005829
GO:0031527
GO:0032433
GO:0030027
GO:0016459
GO:0043005
GO:0043025
GO:0005730
GO:0005886
GO:0001726
GO:0051015
GO:0030898
GO:0005524
GO:0005547
GO:0060002
GO:0030507
GO:0006200
GO:0007411
GO:0030705
GO:0038096
GO:0045087
GO:0008152
GO:0022409
GO:0008360
GO:0051489
Gene3D 1.20.80.10
2.30.29.30
InterPro IPR019749
IPR014352
IPR019748
IPR000299
IPR000048
IPR001609
IPR000857
IPR027417
IPR001849
IPR011993
Pfam PF00373
PF00612
PF00063
PF00784
PF00169
PRINTS PR00193
SMART SM00295
SM00015
SM00242
SM00139
SM00233
SUPFAM SSF47031
SSF52540
PROSITE PS50057
PS50096
PS51456
PS51016
PS50003

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0060002

plus-end directed microfilament motor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P79114

F

Seeded From UniProt

complete

involved_in

GO:0051489

regulation of filopodium assembly

PMID:16894163[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0051015

actin filament binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P79114

F

Seeded From UniProt

complete

part_of

GO:0032433

filopodium tip

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P79114

C

Seeded From UniProt

complete

enables

GO:0030898

actin-dependent ATPase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P79114

F

Seeded From UniProt

complete

involved_in

GO:0030705

cytoskeleton-dependent intracellular transport

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P79114

P

Seeded From UniProt

complete

involved_in

GO:0008360

regulation of cell shape

PMID:16894163[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005547

phosphatidylinositol-3,4,5-trisphosphate binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P79114

F

Seeded From UniProt

complete

enables

GO:0030507

spectrin binding

PMID:23704327[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0043025

neuronal cell body

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:F8VQB6
ensembl:ENSMUSP00000106087

C

Seeded From UniProt

complete

part_of

GO:0043005

neuron projection

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:F8VQB6
ensembl:ENSMUSP00000106087

C

Seeded From UniProt

complete

part_of

GO:0030175

filopodium

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:F8VQB6
ensembl:ENSMUSP00000106087

C

Seeded From UniProt

complete

involved_in

GO:0022409

positive regulation of cell-cell adhesion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:F8VQB6
ensembl:ENSMUSP00000106087

P

Seeded From UniProt

complete

enables

GO:0003774

motor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001609

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001609

F

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000299
InterPro:IPR000857

C

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000159

P

Seeded From UniProt

complete

part_of

GO:0016459

myosin complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001609

C

Seeded From UniProt

complete

involved_in

GO:0038096

Fc-gamma receptor signaling pathway involved in phagocytosis

Reactome:R-HSA-2029480

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-1861595

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

enables

GO:0005516

calmodulin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0112

F

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206
UniProtKB-SubCell:SL-0090

C

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0009

F

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016459

myosin complex

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0518

C

Seeded From UniProt

complete

part_of

GO:0001726

ruffle

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0300

C

Seeded From UniProt

complete

part_of

GO:0030027

lamellipodium

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0291

C

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0091

C

Seeded From UniProt

complete

part_of

GO:0005938

cell cortex

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0138

C

Seeded From UniProt

complete

part_of

GO:0031527

filopodium membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0287

C

Seeded From UniProt

complete

part_of

GO:0032433

filopodium tip

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0470

C

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 Bohil, AB et al. (2006) Myosin-X is a molecular motor that functions in filopodia formation. Proc. Natl. Acad. Sci. U.S.A. 103 12411-6 PubMed GONUTS page
  2. ↑ Papal, S et al. (2013) The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route. Hum. Mol. Genet. 22 3773-88 PubMed GONUTS page
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