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HUMAN:MYL1

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) MYL1
Protein Name(s) Myosin light chain 1/3, skeletal muscle isoform

MLC1/MLC3 MLC1F/MLC3F Myosin light chain alkali 1/2 Myosin light chain A1/A2

External Links
UniProt P05976
EMBL X05450
X05451
M20642
M20643
CR456869
AK311942
AK311892
CH471063
CH471063
BC005318
J05026
CCDS CCDS2390.1
PIR JS0431
S07939
RefSeq NP_524144.1
NP_524146.1
UniGene Hs.187338
ProteinModelPortal P05976
SMR P05976
BioGrid 110716
IntAct P05976
STRING 9606.ENSP00000307280
PhosphoSite P05976
DMDM 127128
SWISS-2DPAGE P05976
MaxQB P05976
PaxDb P05976
PRIDE P05976
Ensembl ENST00000341685
ENST00000352451
GeneID 4632
KEGG hsa:4632
UCSC uc002veb.3
uc002vec.3
CTD 4632
GeneCards GC02M211118
HGNC HGNC:7582
MIM 160780
neXtProt NX_P05976
PharmGKB PA31379
eggNOG COG5126
GeneTree ENSGT00590000082921
HOGENOM HOG000233018
HOVERGEN HBG012180
InParanoid P05976
KO K05738
OMA TNAEINK
OrthoDB EOG7HQN9N
PhylomeDB P05976
TreeFam TF351553
Reactome REACT_16969
ChiTaRS MYL1
GeneWiki MYL1
GenomeRNAi 4632
NextBio 17830
PRO PR:P05976
Proteomes UP000005640
Bgee P05976
CleanEx HS_MYL1
ExpressionAtlas P05976
Genevestigator P05976
GO GO:0005829
GO:0005859
GO:0030016
GO:0030017
GO:0005509
GO:0008307
GO:0060048
GO:0006936
GO:0030049
Gene3D 1.10.238.10
InterPro IPR011992
IPR002048
Pfam PF13405
SMART SM00054
PROSITE PS50222

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0030049

muscle filament sliding

PMID:3904738[1]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0030017

sarcomere

PMID:3904738[1]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030016

myofibril

PMID:8145163[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0008307

structural constituent of muscle

PMID:3904738[1]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006936

muscle contraction

PMID:8145163[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005859

muscle myosin complex

PMID:3904738[1]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0060048

cardiac muscle contraction

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02600
ensembl:ENSRNOP00000017838

P

Seeded From UniProt

complete

part_of

GO:0043292

contractile fiber

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P02600
ensembl:ENSRNOP00000017838

C

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002048

F

Seeded From UniProt

complete

involved_in

GO:0030049

muscle filament sliding

Reactome:R-HSA-390522

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-390598
Reactome:R-HSA-390597
Reactome:R-HSA-390595
Reactome:R-HSA-390593

ECO:0000304

author statement supported by traceable reference used in manual assertion




C

Seeded From UniProt

complete

part_of

GO:0016459

myosin complex

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0518

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Barton, PJ & Buckingham, ME (1985) The myosin alkali light chain proteins and their genes. Biochem. J. 231 249-61 PubMed GONUTS page
  2. 2.0 2.1 Larsson, L & Moss, RL (1993) Maximum velocity of shortening in relation to myosin isoform composition in single fibres from human skeletal muscles. J. Physiol. (Lond.) 472 595-614 PubMed GONUTS page