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HUMAN:MUC16
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | MUC16 (synonyms: CA125) | |
| Protein Name(s) | Mucin-16
MUC-16 Ovarian cancer-related tumor marker CA125 CA-125 Ovarian carcinoma antigen CA125 | |
| External Links | ||
| UniProt | Q8WXI7 | |
| EMBL | AF414442 AF361486 AK128681 | |
| RefSeq | NP_078966.2 | |
| UniGene | Hs.432676 | |
| ProteinModelPortal | Q8WXI7 | |
| BioGrid | 125094 | |
| STRING | 9606.ENSP00000381008 | |
| PhosphoSite | Q8WXI7 | |
| MaxQB | Q8WXI7 | |
| PaxDb | Q8WXI7 | |
| PRIDE | Q8WXI7 | |
| GeneID | 94025 | |
| KEGG | hsa:94025 | |
| CTD | 94025 | |
| GeneCards | GC19M008960 | |
| H-InvDB | HIX0021715 | |
| HGNC | HGNC:15582 | |
| HPA | CAB055172 | |
| MIM | 606154 | |
| neXtProt | NX_Q8WXI7 | |
| PharmGKB | PA31314 | |
| eggNOG | NOG12793 | |
| KO | K16145 | |
| Reactome | REACT_115606 REACT_115835 | |
| ChiTaRS | MUC16 | |
| GeneWiki | CA-125 | |
| GenomeRNAi | 94025 | |
| NextBio | 78314 | |
| PRO | PR:Q8WXI7 | |
| Proteomes | UP000005640 | |
| CleanEx | HS_MUC16 | |
| Genevestigator | Q8WXI7 | |
| GO | GO:0005615 GO:0070062 GO:0019898 GO:0005796 GO:0016021 GO:0005886 GO:0031982 GO:0007155 GO:0044267 GO:0016266 GO:0043687 | |
| Gene3D | 3.30.70.960 | |
| InterPro | IPR028850 IPR000082 | |
| PANTHER | PTHR14672 | |
| Pfam | PF01390 | |
| SMART | SM00200 | |
| SUPFAM | SSF82671 | |
| PROSITE | PS50024 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0031982 |
vesicle |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(CL:0002202) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0070062 |
extracellular exosome |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001831) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0019898 |
extrinsic component of membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007155 |
cell adhesion |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016266 |
O-glycan processing |
Reactome:R-HSA-913709 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
Reactome:R-HSA-8858500 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005796 |
Golgi lumen |
Reactome:R-HSA-981814 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0002223 |
stimulatory C-type lectin receptor signaling pathway |
Reactome:R-HSA-5621481 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kesimer, M et al. (2009) Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. FASEB J. 23 1858-68 PubMed GONUTS page
- ↑ Gonzalez-Begne, M et al. (2009) Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J. Proteome Res. 8 1304-14 PubMed GONUTS page
- ↑ Argüeso, P et al. (2003) MUC16 mucin is expressed by the human ocular surface epithelia and carries the H185 carbohydrate epitope. Invest. Ophthalmol. Vis. Sci. 44 2487-95 PubMed GONUTS page
- ↑ Rump, A et al. (2004) Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion. J. Biol. Chem. 279 9190-8 PubMed GONUTS page
