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HUMAN:MPEG1
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | MPEG1 | |
| Protein Name(s) | Macrophage-expressed gene 1 protein
Macrophage gene 1 protein Mpg-1 | |
| External Links | ||
| UniProt | Q2M385 | |
| EMBL | AK074166 CH471076 BC104997 BC112230 | |
| CCDS | CCDS41650.1 | |
| RefSeq | NP_001034485.1 | |
| UniGene | Hs.744920 | |
| ProteinModelPortal | Q2M385 | |
| IntAct | Q2M385 | |
| STRING | 9606.ENSP00000354335 | |
| PhosphoSite | Q2M385 | |
| DMDM | 121941470 | |
| MaxQB | Q2M385 | |
| PaxDb | Q2M385 | |
| PRIDE | Q2M385 | |
| Ensembl | ENST00000361050 | |
| GeneID | 219972 | |
| KEGG | hsa:219972 | |
| UCSC | uc001nnu.4 | |
| CTD | 219972 | |
| GeneCards | GC11M058975 | |
| HGNC | HGNC:29619 | |
| HPA | HPA046801 | |
| MIM | 610390 | |
| neXtProt | NX_Q2M385 | |
| PharmGKB | PA164723088 | |
| eggNOG | NOG40231 | |
| GeneTree | ENSGT00390000008048 | |
| HOGENOM | HOG000024828 | |
| HOVERGEN | HBG057416 | |
| InParanoid | Q2M385 | |
| OMA | FNFQANT | |
| OrthoDB | EOG7WQ7RW | |
| PhylomeDB | Q2M385 | |
| TreeFam | TF331165 | |
| GenomeRNAi | 219972 | |
| NextBio | 90906 | |
| PRO | PR:Q2M385 | |
| Proteomes | UP000005640 | |
| Bgee | Q2M385 | |
| Genevestigator | Q2M385 | |
| GO | GO:0016021 | |
| InterPro | IPR020864 | |
| Pfam | PF01823 | |
| SMART | SM00457 | |
| PROSITE | PS51412 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0035915 |
pore formation in membrane of other organism |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045335 |
phagocytic vesicle |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042742 |
defense response to bacterium |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0050829 |
defense response to Gram-negative bacterium |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0050830 |
defense response to Gram-positive bacterium |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0050829 |
defense response to Gram-negative bacterium |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042742 |
defense response to bacterium |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002833977 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 McCormack, RM et al. (2015) Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria. Elife 4 PubMed GONUTS page
- ↑ Strbo, N et al. (2019) Single cell analyses reveal specific distribution of anti-bacterial molecule Perforin-2 in human skin and its modulation by wounding and Staphylococcus aureus infection. Exp. Dermatol. 28 225-232 PubMed GONUTS page
- ↑ Fields, KA et al. (2013) Perforin-2 restricts growth of Chlamydia trachomatis in macrophages. Infect. Immun. 81 3045-54 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
